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Zfp28 Gene Detail
Summary
  • Symbol
    Zfp28
  • Name
    zinc finger protein 28
  • Synonyms
    2810438M17Rik, mkr-5, Zfp-28
  • Feature Type
    protein coding gene
  • IDs
    MGI:99175
    NCBI Gene: 22690
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:6386317-6399636 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 3.70 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    499 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99175
 protein coding gene Chr7:6386294-6399914 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0031576
 protein coding gene Chr7:3368077-3383977 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0031584
 protein coding gene Chr7:3477172-3489809 (+)
C3H/HeJ MGP_C3HHeJ_G0031305
 protein coding gene Chr7:3449810-3463467 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032047
 protein coding gene Chr7:3665353-3684110 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029161
 protein coding gene Chr7:3065937-3079102 (+)
CAST/EiJ MGP_CASTEiJ_G0030668
 protein coding gene Chr7:3343809-3355646 (+)
CBA/J MGP_CBAJ_G0031262
 protein coding gene Chr7:3778376-3793671 (+)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0031375
 protein coding gene Chr7:3387622-3403313 (+)
LP/J MGP_LPJ_G0031506
 protein coding gene Chr7:3572848-3590805 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031413
 protein coding gene Chr7:3765206-3781459 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032076
 protein coding gene Chr7:3397043-3415665 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0030222
 protein coding gene Chr7:2982577-2997008 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ZFP28, ZFP28 zinc finger protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZFP28, ZFP28 zinc finger protein
  • Synonyms
    mkr5
  • Links
    NCBI Gene ID: 140612
    neXtProt AC: NX_Q8NHY6
    UniProt: Q8NHY6

  • Chr Location
    19q13.43; chr19:56536947-56556808 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    830
  • Tissues
    77
  • cDNA Data
    30
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22690 NCBI Gene Model | MGI Sequence Detail 13320 C57BL/6J ±  kb
    transcript NM_175247 RefSeq | MGI Sequence Detail 4161 C57BL/6  
    polypeptide P10078 UniProt | EBI | MGI Sequence Detail 825 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 38
      Genomic 5
      cDNA 31
      Primer pair 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGD-MRK-15872, MGD-MRK-15927, MGI:1924084
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 7
      Gene Ontology 4
      Phenotypes 5
    • Earliest
      J:9478 Chowdhury K, et al., Specific and ubiquitous expression of different Zn finger protein genes in the mouse. Nucleic Acids Res. 1988 Nov 11;16(21):9995-10011
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory