Krd Gene Detail

Summary

• Symbol
  Krd
• Name
  kidney and retinal defects
• Synonyms
  Del(19)TgN8052Mm

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:99258
  NCBI Gene: 110026
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 19, Syntenic
• Mapping Data
  3 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  18 phenotypes from 1 allele in 1 genetic background
  7 phenotype references
  

• All Mutations and Alleles
  1
• Transgenic
  1
• Find Mice (IMSR)
  1 strains or lines available

Heterozygotes for a large, transgene-associated deletion exhibit aplastic, hypoplastic and cystic kidneys, retinal defects, growth retardation and variable survival. Homozygotes die in utero.

Sequences &
Gene Models

• NCBI Gene
  110026

Other
Accession IDs

MGD-MRK-16017

References

• Summaries
  All 10

  Phenotypes 7
• Earliest
  J:20807 Keller SA, et al., Kidney and retinal defects (Krd), a transgene-induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus. Genomics. 1994 Sep 15;23(2):309-20
• Latest
  J:59481 Hawes NL, et al., Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes. Mol Vis. 1999 Sep 15;5:22