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Krtap11-1 Gene Detail
Summary
  • Symbol
    Krtap11-1
  • Name
    keratin associated protein 11-1
  • Synonyms
    Hacl1, KAP11.1, PRED29
  • Feature Type
    protein coding gene
  • IDs
    MGI:99447
    NCBI Gene: 16693
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:89367064-89368071 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 51.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99447
 protein coding gene Chr16:89367064-89368071 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023022
 protein coding gene Chr16:90427139-90428146 (-)
A/J MGP_AJ_G0022990
 protein coding gene Chr16:86244120-86245127 (-)
AKR/J MGP_AKRJ_G0022960
 protein coding gene Chr16:88861008-88862015 (-)
BALB/cJ MGP_BALBcJ_G0022992
 protein coding gene Chr16:86763625-86764632 (-)
C3H/HeJ MGP_C3HHeJ_G0022753
 protein coding gene Chr16:89399654-89400661 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023439
 protein coding gene Chr16:93384457-93385464 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020941
 protein coding gene Chr16:83981433-83982440 (-)
CAST/EiJ MGP_CASTEiJ_G0022272
 protein coding gene Chr16:89895462-89896469 (-)
CBA/J MGP_CBAJ_G0022722
 protein coding gene Chr16:97351145-97352152 (-)
DBA/2J MGP_DBA2J_G0022856
 protein coding gene Chr16:86157487-86158494 (-)
FVB/NJ MGP_FVBNJ_G0022830
 protein coding gene Chr16:85265290-85266297 (-)
LP/J MGP_LPJ_G0022926
 protein coding gene Chr16:90111562-90112569 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022851
 protein coding gene Chr16:101997454-101998461 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023457
 protein coding gene Chr16:89345395-89346402 (-)
PWK/PhJ MGP_PWKPhJ_G0022017
 protein coding gene Chr16:86289116-86290123 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021847
 protein coding gene Chr16:88864999-88866004 (-)
WSB/EiJ MGP_WSBEiJ_G0022324
 protein coding gene Chr16:89565347-89566353 (-)



Homology
more
  • Human Ortholog
    KRTAP11-1, keratin associated protein 11-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP11-1, keratin associated protein 11-1
  • Synonyms
    HACL-1, HACL1, KAP11.1
  • Links
    NCBI Gene ID: 337880
    neXtProt AC: NX_Q8IUC1
    UniProt: Q8IUC1

  • Chr Location
    21q22.11; chr21:30880644-30881580 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    797
  • Tissues
    81
  • cDNA Data
    36
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 16693 NCBI Gene Model | MGI Sequence Detail 1008 C57BL/6J ±  kb
transcript NM_001113406 RefSeq | MGI Sequence Detail 1008 C57BL/6  
polypeptide NP_001106877 RefSeq | MGI Sequence Detail 183 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007951 Keratin-associated protein, PMG type
    IPR007659 Keratin, high-sulphur matrix protein
  • GlyGen
    E9Q2E9 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 39
    Genomic 1
    cDNA 36
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-16215, MGI:2146357, MGI:2146590, MGI:2652094
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Phenotypes 6
  • Earliest
    J:17984 Huh N, et al., Isolation and characterization of a novel hair follicle-specific gene, Hacl-1. J Invest Dermatol. 1994 May;102(5):716-20
  • Latest
    J:335294 Redhead Y, et al., Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development. 2023 Apr 15;150(8):dev201077
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory