Igl-C5 Gene Detail

Summary

• Symbol
  Igl-C5
• Name
  immunoglobulin lambda chain, constant region 5

• Feature Type
  gene segment
• IDs
  MGI:99856
  NCBI Gene: 110774
• Alliance
  gene page
• Candidate for QTL
  1 QTL

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• RFLP
  1

Sequences &
Gene Models

• NCBI Gene
  110774

Molecular
Reagents

• All nucleic 4

  Genomic 4

Other
Accession IDs

MGD-MRK-16647

References

• Summaries
  All 4
• Earliest
  J:8712 Kudo A, et al., Organization of the murine Ig-related lambda 5 gene transcribed selectively in pre-B lymphocytes [published erratum appears in EMBO J 1987 Dec 20;6(13):4242]. EMBO J. 1987 Jan;6(1):103-7
• Latest
  J:152405 Kurey I, et al., Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Immunogenetics. 2009 Sep;61(9):619-33

Igl-C5 is Candidate Gene for:

QTL	Genetic Location*	Genome Location (GRCm39)	Reference	QTL Note
Lmr23	Chr16, syntenic	Chr16:12674057-12674200	J:152405	Potential candidated gene mapping near the Lmr23 QTL which mapped with D16Mit73 at 6.8 cM on Chromosome 16 of CcS11/Dem in this map study are: Two clusters of genes that affect B-cell development: Igl-C5, Igll1, Vpreb1, Vpreb2, Iglc1, Iglc3, Iglv1, Iglv2, and Igll1 mapping between 9.8 and 13.0 cM. [Table 9.] A possibly related QTL controlling other infections and co-localizing with the Lmr23 QTL is Dice1, determination of interleukin 4 commitment 1 at 8.0 cM. [Table 10.]

*cM position of peak correlated region/marker