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Nt5m Gene Detail
Summary
  • Symbol
    Nt5m
  • Name
    5',3'-nucleotidase, mitochondrial
  • Synonyms
    2010013E09Rik, dNT-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917127
    NCBI Gene: 103850
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:59730233-59767359 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 37.80 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    933 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917127
 protein coding gene Chr11:59730233-59771794 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018408
 protein coding gene Chr11:59690384-59735971 (+)
A/J MGP_AJ_G0018377
 protein coding gene Chr11:57416580-57458157 (+)
AKR/J MGP_AKRJ_G0018347
 protein coding gene Chr11:59338016-59379720 (+)
BALB/cJ MGP_BALBcJ_G0018348
 protein coding gene Chr11:57764743-57806393 (+)
C3H/HeJ MGP_C3HHeJ_G0018161
 protein coding gene Chr11:59209477-59256661 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018800
 protein coding gene Chr11:61584871-61627044 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016446
 protein coding gene Chr11:54663098-54705146 (+)
CAST/EiJ MGP_CASTEiJ_G0017718
 protein coding gene Chr11:59346258-59389383 (+)
CBA/J MGP_CBAJ_G0018135
 protein coding gene Chr11:64278735-64328440 (+)
DBA/2J MGP_DBA2J_G0018244
 protein coding gene Chr11:57079703-57121506 (+)
FVB/NJ MGP_FVBNJ_G0018235
 protein coding gene Chr11:56737397-56778302 (+)
LP/J MGP_LPJ_G0018317
 protein coding gene Chr11:60292643-60336051 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018259
 protein coding gene Chr11:65369475-65413281 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018841
 protein coding gene Chr11:59366140-59411449 (+)
PWK/PhJ MGP_PWKPhJ_G0017489
 protein coding gene Chr11:57676963-57719345 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017281
 protein coding gene Chr11:59156459-59204566 (+)
WSB/EiJ MGP_WSBEiJ_G0017769
 protein coding gene Chr11:59040671-59086434 (+)



Homology
more
  • Human Ortholog
    NT5M, 5',3'-nucleotidase, mitochondrial
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NT5M, 5',3'-nucleotidase, mitochondrial
  • Synonyms
    dNT-2, dNT2, mdN
  • Links
    NCBI Gene ID: 56953
    neXtProt AC: NX_Q9NPB1
    UniProt: Q9NPB1

  • Chr Location
    17p11.2; chr17:17303335-17347663 (+)  GRCh38
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    829
  • Tissues
    98
  • cDNA Data
    50
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 103850 NCBI Gene Model | MGI Sequence Detail 37127 C57BL/6J ±  kb
transcript NM_001418354 RefSeq | MGI Sequence Detail 1428 C57BL/6  
polypeptide Q8VCE6 UniProt | EBI | MGI Sequence Detail 220 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    Genomic 1
    cDNA 50

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144290
References
more
  • Summaries
    All 45
    Developmental Gene Expression 2
    Diseases 3
    Gene Ontology 5
    Phenotypes 21
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:185284 Lacaria M, et al., Enriched rearing improves behavioral responses of an animal model for CNV-based autistic-like traits. Hum Mol Genet. 2012 Jul 15;21(14):3083-96
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory