Syt4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Syt4
synaptotagmin IV
MGI:101759

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0005509	calcium ion binding	IDA	J:91437
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	IDA	J:235272
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	IBA	J:265628
Molecular Function	GO:0030276	clathrin binding	ISO	J:155856
Molecular Function	GO:0030276	clathrin binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0001786	phosphatidylserine binding	ISO	J:155856
Molecular Function	GO:0001786	phosphatidylserine binding	IBA	J:265628
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:155856
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:155856
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:0000149	SNARE binding	IBA	J:265628
Molecular Function	GO:0019905	syntaxin binding	ISO	J:155856
Molecular Function	GO:0017075	syntaxin-1 binding	ISO	J:155856
Molecular Function	GO:0030348	syntaxin-3 binding	ISO	J:155856
Cellular Component	GO:0097449	astrocyte projection	IDA	J:91437
Cellular Component	GO:0097449	astrocyte projection	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:235267
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:161262
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IDA	J:235267
Cellular Component	GO:0030425	dendrite	IDA	J:161262
Cellular Component	GO:0030425	dendrite	IDA	J:235258
Cellular Component	GO:0031045	dense core granule	IDA	J:146181
Cellular Component	GO:0031045	dense core granule	ISO	J:155856
Cellular Component	GO:0031045	dense core granule	IDA	J:136185
Cellular Component	GO:0070382	exocytic vesicle	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:161262
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:161262
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:161262
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:235267
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0016020	membrane	TAS	J:19903
Cellular Component	GO:0016020	membrane	NAS	J:23959
Cellular Component	GO:1990742	microvesicle	IDA	J:146181
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:91437
Cellular Component	GO:0044306	neuron projection terminus	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IDA	J:235258
Cellular Component	GO:0098992	neuronal dense core vesicle	ISO	J:155856
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	ISO	J:155856
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IDA	J:146181
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IPI	J:146181
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IPI	J:146181
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IDA	J:146181
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IEP	J:146181
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IDA	J:146181
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IDA	J:161262
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IDA	J:161262
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	IDA	J:161262
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:91437
Cellular Component	GO:0005886	plasma membrane	IDA	J:235267
Cellular Component	GO:0098794	postsynapse	NAS	J:161262
Cellular Component	GO:0098793	presynapse	IMP	J:161262
Cellular Component	GO:0098793	presynapse	NAS	J:161262
Cellular Component	GO:0030667	secretory granule membrane	ISO	J:155856
Cellular Component	GO:0036477	somatodendritic compartment	IDA	J:235267
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0031982	vesicle	IDA	J:161262
Cellular Component	GO:0031982	vesicle	IDA	J:235267
Biological Process	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071277	cellular response to calcium ion	IBA	J:265628
Biological Process	GO:0099519	dense core granule cytoskeletal transport	IMP	J:254524
Biological Process	GO:0099519	dense core granule cytoskeletal transport	ISO	J:155856
Biological Process	GO:0006887	exocytosis	IEA	J:72247
Biological Process	GO:0007613	memory	IMP	J:235426
Biological Process	GO:0045955	negative regulation of calcium ion-dependent exocytosis	ISO	J:155856
Biological Process	GO:0033604	negative regulation of catecholamine secretion	ISO	J:164563
Biological Process	GO:0033604	negative regulation of catecholamine secretion	ISO	J:155856
Biological Process	GO:1905414	negative regulation of dense core granule exocytosis	ISO	J:155856
Biological Process	GO:0046929	negative regulation of neurotransmitter secretion	ISO	J:155856
Biological Process	GO:0050709	negative regulation of protein secretion	IMP	J:161262
Biological Process	GO:1905433	negative regulation of retrograde trans-synaptic signaling by neuropeptide	IMP	J:161262
Biological Process	GO:0048174	negative regulation of short-term neuronal synaptic plasticity	IMP	J:235426
Biological Process	GO:2000301	negative regulation of synaptic vesicle exocytosis	IMP	J:161262
Biological Process	GO:0031339	negative regulation of vesicle fusion	ISO	J:155856
Biological Process	GO:0007269	neurotransmitter secretion	IDA	J:91437
Biological Process	GO:1903861	positive regulation of dendrite extension	ISO	J:164563
Biological Process	GO:1905415	positive regulation of dense core granule exocytosis	IMP	J:136185
Biological Process	GO:0014049	positive regulation of glutamate secretion	IMP	J:91437
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	TAS	J:19903
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	IMP	J:156713
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	IMP	J:146181
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	IBA	J:265628
Biological Process	GO:0014059	regulation of dopamine secretion	IMP	J:235258
Biological Process	GO:0014059	regulation of dopamine secretion	IBA	J:265628
Biological Process	GO:0030100	regulation of endocytosis	IMP	J:146181
Biological Process	GO:0030100	regulation of endocytosis	ISO	J:155856
Biological Process	GO:0150044	regulation of postsynaptic dense core vesicle exocytosis	IMP	J:161262
Biological Process	GO:0150044	regulation of postsynaptic dense core vesicle exocytosis	EXP	J:161262
Biological Process	GO:0150044	regulation of postsynaptic dense core vesicle exocytosis	IMP	J:161262
Biological Process	GO:0150044	regulation of postsynaptic dense core vesicle exocytosis	IDA	J:161262
Biological Process	GO:0150044	regulation of postsynaptic dense core vesicle exocytosis	IDA	J:161262
Biological Process	GO:0150044	regulation of postsynaptic dense core vesicle exocytosis	IDA	J:161262
Biological Process	GO:0150044	regulation of postsynaptic dense core vesicle exocytosis	IDA	J:161262
Biological Process	GO:0150035	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	IMP	J:161262
Biological Process	GO:0150035	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	EXP	J:161262
Biological Process	GO:0150035	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:161262
Biological Process	GO:0150035	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:161262
Biological Process	GO:0150035	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:161262
Biological Process	GO:0150035	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	IDA	J:161262
Biological Process	GO:0150035	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	IMP	J:161262
Biological Process	GO:0031338	regulation of vesicle fusion	ISO	J:155856
Biological Process	GO:0031338	regulation of vesicle fusion	IMP	J:146181
Biological Process	GO:0061792	secretory granule maturation	ISO	J:155856
Biological Process	GO:0048489	synaptic vesicle transport	TAS	J:19903
Biological Process	GO:0006906	vesicle fusion	IBA	J:265628
Biological Process	GO:0061782	vesicle fusion with vesicle	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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