GO Annotations Graph

• Symbol: Cd86
• Name: CD86 antigen
• ID: MGI:101773

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:191189
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:87421
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:91939
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:93933
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:143981
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:86264
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:87420
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:93933
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IDA	J:115064
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0007202	activation of phospholipase C activity	IDA	J:191189
Biological Process	GO:1990051	activation of protein kinase C activity	IDA	J:191189
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0042113	B cell activation	IDA	J:191189
Biological Process	GO:0042113	B cell activation	IDA	J:152781
Biological Process	GO:0023035	CD40 signaling pathway	IDA	J:191189
Biological Process	GO:0007166	cell surface receptor signaling pathway	IBA	J:265628
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IBA	J:265628
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IDA	J:143745
Biological Process	GO:0051607	defense response to virus	IDA	J:143981
Biological Process	GO:0006955	immune response	IBA	J:265628
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0002668	negative regulation of T cell anergy	ISO	J:155856
Biological Process	GO:0042130	negative regulation of T cell proliferation	IBA	J:265628
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	ISO	J:155856
Biological Process	GO:0002639	positive regulation of immunoglobulin production	IDA	J:191189
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	IDA	J:191189
Biological Process	GO:0042102	positive regulation of T cell proliferation	ISO	J:155856
Biological Process	GO:0042102	positive regulation of T cell proliferation	IBA	J:265628
Biological Process	GO:0042102	positive regulation of T cell proliferation	IGI	J:205441
Biological Process	GO:0042110	T cell activation	ISO	J:164563
Biological Process	GO:0031295	T cell costimulation	IBA	J:265628
Biological Process	GO:0034138	toll-like receptor 3 signaling pathway	IMP	J:222664
Biological Process	GO:0002224	toll-like receptor signaling pathway	IDA	J:152781