GO Annotations Graph

• Symbol: Plk4
• Name: polo like kinase 4
• ID: MGI:101783

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:117704
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:152657
Molecular Function	GO:0005515	protein binding	IPI	J:117704
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:152657
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005814	centriole	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0098536	deuterosome	IDA	J:203522
Cellular Component	GO:0005730	nucleolus	IDA	J:152657
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0120098	procentriole	ISO	J:164563
Cellular Component	GO:0120099	procentriole replication complex	ISO	J:164563
Cellular Component	GO:0001741	XY body	IDA	J:199766
Biological Process	GO:0007099	centriole replication	IMP	J:203522
Biological Process	GO:0007099	centriole replication	NAS	J:131391
Biological Process	GO:0007099	centriole replication	ISO	J:164563
Biological Process	GO:0060271	cilium assembly	ISO	J:164563
Biological Process	GO:0098535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	IMP	J:203522
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0046601	positive regulation of centriole replication	ISO	J:164563
Biological Process	GO:0046601	positive regulation of centriole replication	ISO	J:197278
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0060707	trophoblast giant cell differentiation	IMP	J:152657