GO Annotations Graph

• Symbol: Nes
• Name: nestin
• ID: MGI:101784

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031730	CCR5 chemokine receptor binding	ISO	J:155856
Molecular Function	GO:0031730	CCR5 chemokine receptor binding	IBA	J:265628
Molecular Function	GO:0019215	intermediate filament binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:196061
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:87375
Cellular Component	GO:0005737	cytoplasm	IDA	J:139991
Cellular Component	GO:0005737	cytoplasm	IDA	J:196061
Cellular Component	GO:0005737	cytoplasm	IDA	J:149670
Cellular Component	GO:0005737	cytoplasm	IDA	J:142500
Cellular Component	GO:0005737	cytoplasm	IDA	J:130044
Cellular Component	GO:0005882	intermediate filament	ISO	J:155856
Cellular Component	GO:0005882	intermediate filament	IBA	J:265628
Cellular Component	GO:0005882	intermediate filament	IDA	J:44290
Cellular Component	GO:0045111	intermediate filament cytoskeleton	ISO	J:164563
Biological Process	GO:0048858	cell projection morphogenesis	IMP	J:112200
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043086	negative regulation of catalytic activity	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:168641
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IDA	J:83153
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:168641
Biological Process	GO:0030844	positive regulation of intermediate filament depolymerization	ISO	J:155856
Biological Process	GO:0030844	positive regulation of intermediate filament depolymerization	IBA	J:265628
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	ISO	J:155856
Biological Process	GO:0072089	stem cell proliferation	ISO	J:164563