GO Annotations Graph

• Symbol: Mtf1
• Name: metal response element binding transcription factor 1
• ID: MGI:101786

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:65477
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:116529
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:48216
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:65478
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:65477
Molecular Function	GO:0035035	histone acetyltransferase binding	IPI	J:142329
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:142329
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:212038
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5660470
Cellular Component	GO:0005634	nucleus	IDA	J:212038
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IC	J:65477
Biological Process	GO:1990079	cartilage homeostasis	IMP	J:212038
Biological Process	GO:0071294	cellular response to zinc ion	IDA	J:212038
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:212038
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:65477
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:48216
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:65478
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:197394
Biological Process	GO:0046686	response to cadmium ion	IMP	J:48216
Biological Process	GO:0006979	response to oxidative stress	IMP	J:48216