GO Annotations Graph

• Symbol: Usp15
• Name: ubiquitin specific peptidase 15
• ID: MGI:101857

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:155856
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IDA	J:81454
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0101005	deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0101005	deubiquitinase activity	IMP	J:287555
Molecular Function	GO:0008047	enzyme activator activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:1990380	K48-linked deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0046332	SMAD binding	ISO	J:164563
Molecular Function	GO:0005160	transforming growth factor beta receptor binding	ISO	J:164563
Molecular Function	GO:0061649	ubiquitin modification-dependent histone binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:164563
Biological Process	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination	ISO	J:164563
Biological Process	GO:0035520	monoubiquitinated protein deubiquitination	ISO	J:164563
Biological Process	GO:1905035	negative regulation of antifungal innate immune response	ISO	J:164563
Biological Process	GO:0060389	pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:1900246	positive regulation of RIG-I signaling pathway	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	ISO	J:155856
Biological Process	GO:0016579	protein deubiquitination	IMP	J:287555
Biological Process	GO:1990167	protein K27-linked deubiquitination	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:1902238	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	IMP	J:287555
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	J:72247