GO Annotations Graph

• Symbol: Pou5f1
• Name: POU domain, class 5, transcription factor 1
• ID: MGI:101893

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:138113
Molecular Function	GO:0003682	chromatin binding	IDA	J:99361
Molecular Function	GO:0003682	chromatin binding	IDA	J:168828
Molecular Function	GO:0003682	chromatin binding	IDA	J:168828
Molecular Function	GO:0003682	chromatin binding	IDA	J:99361
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:206154
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:206154
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:196872
Molecular Function	GO:0019955	cytokine binding	IDA	J:196872
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:10293
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:210931
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:281188
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:104800
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:259122
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:204034
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:195215
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:10293
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:82741
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:10568
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:10576
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:168207
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:197716
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:154826
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:170271
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0071837	HMG box domain binding	ISO	J:155856
Molecular Function	GO:0070577	lysine-acetylated histone binding	IDA	J:198818
Molecular Function	GO:0035198	miRNA binding	ISO	J:164563
Molecular Function	GO:0070974	POU domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:191743
Molecular Function	GO:0005515	protein binding	IPI	J:170044
Molecular Function	GO:0005515	protein binding	IPI	J:154829
Molecular Function	GO:0005515	protein binding	IPI	J:175308
Molecular Function	GO:0005515	protein binding	IPI	J:255341
Molecular Function	GO:0005515	protein binding	IPI	J:240581
Molecular Function	GO:0005515	protein binding	IPI	J:170271
Molecular Function	GO:0005515	protein binding	IPI	J:182366
Molecular Function	GO:0005515	protein binding	IPI	J:204034
Molecular Function	GO:0005515	protein binding	IPI	J:184123
Molecular Function	GO:0005515	protein binding	IPI	J:131445
Molecular Function	GO:0005515	protein binding	IPI	J:161286
Molecular Function	GO:0005515	protein binding	IPI	J:259122
Molecular Function	GO:0005515	protein binding	IPI	J:133013
Molecular Function	GO:0005515	protein binding	IPI	J:161094
Molecular Function	GO:0005515	protein binding	IPI	J:168284
Molecular Function	GO:0005515	protein binding	IPI	J:104800
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:123604
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:100846
Molecular Function	GO:0005515	protein binding	IPI	J:29675
Molecular Function	GO:0005515	protein binding	IPI	J:227373
Molecular Function	GO:0005515	protein binding	IPI	J:100846
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:210931
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:100846
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:100846
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:100846
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IGI	J:100846
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:82741
Molecular Function	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	IDA	J:125698
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:140350
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:204034
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:198818
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:37111
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:107560
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:48570
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:136286
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:154112
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:154112
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:168146
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:154112
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:20571
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:27203
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:132750
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:154112
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:125698
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:154826
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:221330
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:168207
Cellular Component	GO:0000785	chromatin	IDA	J:196872
Cellular Component	GO:0000785	chromatin	IDA	J:198818
Cellular Component	GO:0005737	cytoplasm	IMP	J:259122
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:199456
Cellular Component	GO:0005737	cytoplasm	IDA	J:200667
Cellular Component	GO:0005737	cytoplasm	IDA	J:21487
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0001674	female germ cell nucleus	IDA	J:46643
Cellular Component	GO:0001674	female germ cell nucleus	IDA	J:21487
Cellular Component	GO:0043073	germ cell nucleus	IDA	J:82966
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:46643
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IDA	J:200667
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IDA	J:170271
Cellular Component	GO:0005634	nucleus	IDA	J:140350
Cellular Component	GO:0005634	nucleus	IDA	J:170599
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IMP	J:195215
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IMP	J:259122
Cellular Component	GO:0005634	nucleus	IDA	J:319899
Cellular Component	GO:0005634	nucleus	IDA	J:198818
Cellular Component	GO:0005634	nucleus	IC	J:82741
Cellular Component	GO:0005634	nucleus	IDA	J:199456
Cellular Component	GO:0005634	nucleus	IDA	J:126330
Cellular Component	GO:0005634	nucleus	IDA	J:21487
Cellular Component	GO:0005634	nucleus	IDA	J:158887
Cellular Component	GO:0005634	nucleus	IDA	J:108385
Cellular Component	GO:0005634	nucleus	IDA	J:86143
Cellular Component	GO:0005634	nucleus	IDA	J:189004
Cellular Component	GO:0005634	nucleus	IDA	J:133713
Cellular Component	GO:0005634	nucleus	IDA	J:99569
Cellular Component	GO:0005634	nucleus	IDA	J:136803
Cellular Component	GO:0005634	nucleus	IDA	J:143129
Cellular Component	GO:0005634	nucleus	IDA	J:136803
Cellular Component	GO:0005634	nucleus	IDA	J:46643
Cellular Component	GO:0005634	nucleus	IDA	J:94395
Cellular Component	GO:0005634	nucleus	IDA	J:90627
Cellular Component	GO:0005634	nucleus	IDA	J:134633
Cellular Component	GO:0005634	nucleus	IDA	J:222297
Cellular Component	GO:0005634	nucleus	IDA	J:46643
Cellular Component	GO:0005634	nucleus	IDA	J:117056
Cellular Component	GO:0005634	nucleus	IDA	J:227373
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:104800
Cellular Component	GO:0005634	nucleus	IDA	J:90627
Cellular Component	GO:0005634	nucleus	IDA	J:132750
Cellular Component	GO:0005634	nucleus	IDA	J:156932
Cellular Component	GO:0005634	nucleus	IDA	J:204143
Cellular Component	GO:0005634	nucleus	IDA	J:194646
Cellular Component	GO:0005634	nucleus	IDA	J:137356
Cellular Component	GO:0005634	nucleus	IDA	J:155582
Cellular Component	GO:0005634	nucleus	IDA	J:137356
Cellular Component	GO:0005634	nucleus	IDA	J:223575
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:123604
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:132750
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:197716
Cellular Component	GO:0017053	transcription repressor complex	IDA	J:104800
Biological Process	GO:0001824	blastocyst development	IEP	J:170599
Biological Process	GO:0001832	blastocyst growth	IGI	J:203796
Biological Process	GO:0045165	cell fate commitment	IMP	J:51139
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0001712	ectodermal cell fate commitment	IDA	J:61492
Biological Process	GO:0001711	endodermal cell fate commitment	IDA	J:61492
Biological Process	GO:0001714	endodermal cell fate specification	ISO	J:168146
Biological Process	GO:0010467	gene expression	IMP	J:290525
Biological Process	GO:0010467	gene expression	IMP	J:124021
Biological Process	GO:0030718	germ-line stem cell population maintenance	IMP	J:95317
Biological Process	GO:0001710	mesodermal cell fate commitment	IDA	J:61492
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045955	negative regulation of calcium ion-dependent exocytosis	IDA	J:10568
Biological Process	GO:0045596	negative regulation of cell differentiation	IGI	J:104800
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:10293
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:196872
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:104800
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:104800
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:104800
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:104800
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:259122
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:10293
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:196872
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:125698
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:210931
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:195215
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:123604
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:116485
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:99361
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:29675
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:100846
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:100846
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:48570
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:48570
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:99361
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:100846
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:100846
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:168146
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:10576
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	IDA	J:281188
Biological Process	GO:0009786	regulation of asymmetric cell division	IEP	J:170599
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:82741
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:168207
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0010033	response to organic substance	IDA	J:136286
Biological Process	GO:0032526	response to retinoic acid	IDA	J:136286
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:164442
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:51139
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:86143
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:111554
Biological Process	GO:0048863	stem cell differentiation	IMP	J:195215
Biological Process	GO:0048863	stem cell differentiation	IMP	J:259122
Biological Process	GO:0048863	stem cell differentiation	IDA	J:156932
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:195215
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:198818
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:10293
Biological Process	GO:0001829	trophectodermal cell differentiation	IGI	J:104800
Biological Process	GO:0001829	trophectodermal cell differentiation	IGI	J:104800
Biological Process	GO:0001830	trophectodermal cell fate commitment	IDA	J:61492