GO Annotations Graph

• Symbol: Tnc
• Name: tenascin C
• ID: MGI:101922

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0001968	fibronectin binding	ISO	J:73065
Molecular Function	GO:0045545	syndecan binding	ISO	J:33445
Cellular Component	GO:0005604	basement membrane	IDA	J:13269
Cellular Component	GO:0005604	basement membrane	IDA	J:144885
Cellular Component	GO:0005604	basement membrane	IDA	J:37867
Cellular Component	GO:0005604	basement membrane	IDA	J:13269
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:213088
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IDA	J:213088
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0031012	extracellular matrix	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2752145
Cellular Component	GO:0005576	extracellular region	IDA	J:35308
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005614	interstitial matrix	IDA	J:74274
Cellular Component	GO:0098966	perisynaptic extracellular matrix	IBA	J:265628
Cellular Component	GO:0098966	perisynaptic extracellular matrix	IDA	J:263376
Cellular Component	GO:0098966	perisynaptic extracellular matrix	EXP	J:263376
Cellular Component	GO:0090733	tenascin complex	IPI	J:87910
Biological Process	GO:0060447	bud outgrowth involved in lung branching	ISO	J:155856
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	IMP	J:144885
Biological Process	GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	IMP	J:144885
Biological Process	GO:0002009	morphogenesis of an epithelium	IMP	J:144885
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:155856
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:47799
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0014012	peripheral nervous system axon regeneration	IMP	J:104316
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:152705
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:152705
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:152705
Biological Process	GO:0060740	prostate gland epithelium morphogenesis	IMP	J:144885
Biological Process	GO:0030155	regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0030155	regulation of cell adhesion	IBA	J:265628
Biological Process	GO:0001558	regulation of cell growth	ISO	J:164563
Biological Process	GO:0030334	regulation of cell migration	NAS	J:320279
Biological Process	GO:0042127	regulation of cell population proliferation	IEA	J:72247
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:314848
Biological Process	GO:0009611	response to wounding	ISO	J:164563