Slc9a1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Slc9a1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
MGI:102462

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015297	antiporter activity	IEA	J:60000
Molecular Function	GO:0048306	calcium-dependent protein binding	ISO	J:164563
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0043167	ion binding	ISO	J:164563
Molecular Function	GO:0015386	potassium:proton antiporter activity	IBA	J:265628
Molecular Function	GO:0030346	protein phosphatase 2B binding	ISO	J:164563
Molecular Function	GO:0015385	sodium:proton antiporter activity	ISO	J:155856
Molecular Function	GO:0015385	sodium:proton antiporter activity	ISO	J:164563
Molecular Function	GO:0015385	sodium:proton antiporter activity	IBA	J:265628
Molecular Function	GO:0015385	sodium:proton antiporter activity	ISO	J:323605
Molecular Function	GO:0015385	sodium:proton antiporter activity	IMP	J:202055
Molecular Function	GO:0015385	sodium:proton antiporter activity	IDA	J:80600
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:176751
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	TAS	J:80600
Cellular Component	GO:0090533	cation-transporting ATPase complex	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:82898
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:323605
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Cellular Component	GO:1990351	transporter complex	ISO	J:323611
Cellular Component	GO:1990351	transporter complex	IDA	J:199873
Biological Process	GO:0055007	cardiac muscle cell differentiation	IMP	J:146335
Biological Process	GO:0071468	cellular response to acidic pH	ISO	J:164563
Biological Process	GO:0071872	cellular response to epinephrine stimulus	ISO	J:164563
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:155856
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:155856
Biological Process	GO:0009790	embryo development	IMP	J:202055
Biological Process	GO:0030214	hyaluronan catabolic process	ISO	J:323605
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:164563
Biological Process	GO:0006812	monoatomic cation transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0070997	neuron death	ISO	J:155856
Biological Process	GO:0045760	positive regulation of action potential	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	ISO	J:164563
Biological Process	GO:1903281	positive regulation of calcium:sodium antiporter activity	ISO	J:164563
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:155856
Biological Process	GO:1902533	positive regulation of intracellular signal transduction	ISO	J:155856
Biological Process	GO:0035794	positive regulation of mitochondrial membrane permeability	ISO	J:155856
Biological Process	GO:0098735	positive regulation of the force of heart contraction	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:1902600	proton transmembrane transport	ISO	J:164563
Biological Process	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	ISO	J:164563
Biological Process	GO:0051453	regulation of intracellular pH	ISO	J:164563
Biological Process	GO:0051453	regulation of intracellular pH	ISO	J:155856
Biological Process	GO:0051453	regulation of intracellular pH	IBA	J:265628
Biological Process	GO:0006885	regulation of pH	ISO	J:164563
Biological Process	GO:0006885	regulation of pH	IMP	J:60484
Biological Process	GO:0006885	regulation of pH	IDA	J:80600
Biological Process	GO:0051930	regulation of sensory perception of pain	ISO	J:155856
Biological Process	GO:0002026	regulation of the force of heart contraction	ISO	J:155856
Biological Process	GO:0086092	regulation of the force of heart contraction by cardiac conduction	ISO	J:164563
Biological Process	GO:0010447	response to acidic pH	ISO	J:155856
Biological Process	GO:0010447	response to acidic pH	ISO	J:164563
Biological Process	GO:0010447	response to acidic pH	IMP	J:60484
Biological Process	GO:0010447	response to acidic pH	IMP	J:60484
Biological Process	GO:0035994	response to muscle stretch	ISO	J:164563
Biological Process	GO:0014070	response to organic cyclic compound	ISO	J:155856
Biological Process	GO:0098719	sodium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0098719	sodium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0006814	sodium ion transport	IDA	J:80600
Biological Process	GO:0048863	stem cell differentiation	IMP	J:146335
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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