Nfatc2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
MGI:102463

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:206594
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:15443
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:94240
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:208305
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:80577
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0019902	phosphatase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:190673
Molecular Function	GO:0005515	protein binding	IPI	J:247860
Molecular Function	GO:0005515	protein binding	IPI	J:154929
Molecular Function	GO:0005515	protein binding	IPI	J:204781
Molecular Function	GO:0005515	protein binding	IPI	J:174501
Molecular Function	GO:0005515	protein binding	IPI	J:51755
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:80577
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:94240
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:15443
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:77778
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:37154
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:28305
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:28305
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:28305
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:28305
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:154929
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:208305
Molecular Function	GO:0008134	transcription factor binding	IBA	J:265628
Molecular Function	GO:0008134	transcription factor binding	IPI	J:206594
Cellular Component	GO:0000785	chromatin	IDA	J:208305
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:94240
Cellular Component	GO:0005737	cytoplasm	IDA	J:197109
Cellular Component	GO:0005737	cytoplasm	IDA	J:174389
Cellular Component	GO:0005737	cytoplasm	IDA	J:33570
Cellular Component	GO:0005737	cytoplasm	IDA	J:77729
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2025936
Cellular Component	GO:0005829	cytosol	IDA	J:282820
Cellular Component	GO:0005829	cytosol	IDA	J:15443
Cellular Component	GO:0005829	cytosol	IDA	J:37134
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-2025936
Cellular Component	GO:0005634	nucleus	IDA	J:154929
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:190980
Cellular Component	GO:0005634	nucleus	IDA	J:94240
Cellular Component	GO:0005634	nucleus	IDA	J:33570
Cellular Component	GO:0005634	nucleus	IDA	J:190980
Cellular Component	GO:0005634	nucleus	IDA	J:282820
Cellular Component	GO:0005634	nucleus	IDA	J:15443
Cellular Component	GO:0005634	nucleus	IDA	J:197109
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:217434
Cellular Component	GO:0005634	nucleus	IDA	J:171469
Cellular Component	GO:1990904	ribonucleoprotein complex	IDA	J:174389
Cellular Component	GO:0035976	transcription factor AP-1 complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:151652
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:15443
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:151652
Biological Process	GO:0050853	B cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	IBA	J:265628
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	IGI	J:142475
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0001816	cytokine production	IBA	J:265628
Biological Process	GO:0001816	cytokine production	IDA	J:97353
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0014904	myotube cell development	IMP	J:142475
Biological Process	GO:0098781	ncRNA transcription	IMP	J:324695
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:80577
Biological Process	GO:1905064	negative regulation of vascular associated smooth muscle cell differentiation	ISO	J:164563
Biological Process	GO:0030890	positive regulation of B cell proliferation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:97353
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:154929
Biological Process	GO:1901741	positive regulation of myoblast fusion	IMP	J:107688
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:208305
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:94240
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:94240
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:77778
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:206594
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:15443
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:206594
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:319998
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:164563
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:206594
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:206594

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24