Nfatc1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nfatc1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
MGI:102469

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:206594
Molecular Function	GO:0003677	DNA binding	IDA	J:202853
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:180479
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:180479
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:180479
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:168211
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:143956
Molecular Function	GO:0048273	mitogen-activated protein kinase p38 binding	IPI	J:180479
Molecular Function	GO:0003676	nucleic acid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:177735
Molecular Function	GO:0005515	protein binding	IPI	J:218000
Molecular Function	GO:0005515	protein binding	IPI	J:297319
Molecular Function	GO:0005515	protein binding	IPI	J:154803
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:180479
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:138546
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:180479
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:87791
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:28305
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:155856
Molecular Function	GO:0008134	transcription factor binding	IBA	J:265628
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:180479
Cellular Component	GO:0005737	cytoplasm	IDA	J:159586
Cellular Component	GO:0005737	cytoplasm	IDA	J:80323
Cellular Component	GO:0005737	cytoplasm	IDA	J:77729
Cellular Component	GO:0005737	cytoplasm	IDA	J:177648
Cellular Component	GO:0005737	cytoplasm	IDA	J:80323
Cellular Component	GO:0005737	cytoplasm	IDA	J:63214
Cellular Component	GO:0005737	cytoplasm	IDA	J:80323
Cellular Component	GO:0005737	cytoplasm	IDA	J:154803
Cellular Component	GO:0005737	cytoplasm	IDA	J:80323
Cellular Component	GO:0005737	cytoplasm	IDA	J:80323
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:159586
Cellular Component	GO:0005634	nucleus	IDA	J:235251
Cellular Component	GO:0005634	nucleus	IDA	J:228311
Cellular Component	GO:0005634	nucleus	IDA	J:297319
Cellular Component	GO:0005634	nucleus	IDA	J:180479
Cellular Component	GO:0005634	nucleus	IDA	J:46398
Cellular Component	GO:0005634	nucleus	IDA	J:85495
Cellular Component	GO:0005634	nucleus	IDA	J:143917
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:149253
Cellular Component	GO:0005634	nucleus	IDA	J:73985
Cellular Component	GO:0005634	nucleus	IDA	J:100441
Cellular Component	GO:0005634	nucleus	IDA	J:46398
Cellular Component	GO:0005634	nucleus	IDA	J:46399
Cellular Component	GO:0005634	nucleus	IDA	J:46398
Cellular Component	GO:0005634	nucleus	IDA	J:212598
Cellular Component	GO:0005634	nucleus	IDA	J:177648
Cellular Component	GO:0005634	nucleus	IDA	J:63214
Cellular Component	GO:0005634	nucleus	IDA	J:154803
Cellular Component	GO:0005634	nucleus	IDA	J:171374
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:151652
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:151652
Biological Process	GO:0003176	aortic valve development	IMP	J:183686
Biological Process	GO:0003180	aortic valve morphogenesis	IMP	J:46398
Biological Process	GO:0002337	B-1a B cell differentiation	IMP	J:86543
Biological Process	GO:0060854	branching involved in lymph vessel morphogenesis	IMP	J:149253
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	ISO	J:164563
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	IBA	J:265628
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	IMP	J:149253
Biological Process	GO:0006816	calcium ion transport	IMP	J:84257
Biological Process	GO:0044838	cell quiescence	IMP	J:212598
Biological Process	GO:0001816	cytokine production	IBA	J:265628
Biological Process	GO:0003197	endocardial cushion development	IGI	J:183686
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:92515
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	IMP	J:84257
Biological Process	GO:0007507	heart development	IMP	J:92515
Biological Process	GO:0007507	heart development	IMP	J:92515
Biological Process	GO:0061384	heart trabecula morphogenesis	IMP	J:46399
Biological Process	GO:0003170	heart valve development	IMP	J:183686
Biological Process	GO:0003179	heart valve morphogenesis	IMP	J:46399
Biological Process	GO:0035556	intracellular signal transduction	ISO	J:87682
Biological Process	GO:0043616	keratinocyte proliferation	IMP	J:212598
Biological Process	GO:0001946	lymphangiogenesis	IGI	J:149253
Biological Process	GO:0001946	lymphangiogenesis	IGI	J:149253
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	IMP	J:212598
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	IDA	J:154803
Biological Process	GO:2000647	negative regulation of stem cell proliferation	IMP	J:212598
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:154803
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:154803
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:212598
Biological Process	GO:1905064	negative regulation of vascular associated smooth muscle cell differentiation	ISO	J:164563
Biological Process	GO:0030316	osteoclast differentiation	IGI	J:177648
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:87682
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:193006
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:180479
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:180479
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:123002
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:149253
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:215013
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:149253
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:145836
Biological Process	GO:0003177	pulmonary valve development	IMP	J:183686
Biological Process	GO:0003184	pulmonary valve morphogenesis	IMP	J:46398
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0042634	regulation of hair cycle	IMP	J:212598
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:178104
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:1905314	semi-lunar valve development	IMP	J:183686
Biological Process	GO:0072089	stem cell proliferation	IMP	J:212598
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:212598
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:154803
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:149253
Biological Process	GO:0006366	transcription by RNA polymerase II	IDA	J:154803
Biological Process	GO:0014883	transition between fast and slow fiber	IMP	J:143956
Biological Process	GO:0060412	ventricular septum morphogenesis	IMP	J:46398

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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