GO Annotations Graph

• Symbol: Cacnb1
• Name: calcium channel, voltage-dependent, beta 1 subunit
• ID: MGI:102522

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IGI	J:75166
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0051219	phosphoprotein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:28892
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IDA	J:28892
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:103273
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:37052
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-525831
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0098793	presynapse	IDA	J:161676
Cellular Component	GO:0098793	presynapse	IDA	J:161676
Cellular Component	GO:0098793	presynapse	IMP	J:161676
Cellular Component	GO:0098793	presynapse	IDA	J:161676
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:37052
Cellular Component	GO:0030315	T-tubule	IDA	J:37052
Cellular Component	GO:0005891	voltage-gated calcium channel complex	ISO	J:155856
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IBA	J:265628
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IDA	J:57712
Biological Process	GO:0070588	calcium ion transmembrane transport	NAS	J:320086
Biological Process	GO:0006816	calcium ion transport	IMP	J:103273
Biological Process	GO:0006816	calcium ion transport	IMP	J:37052
Biological Process	GO:1904646	cellular response to amyloid-beta	ISO	J:164563
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0007528	neuromuscular junction development	IBA	J:265628
Biological Process	GO:0045933	positive regulation of muscle contraction	NAS	J:320086
Biological Process	GO:0006612	protein targeting to membrane	IMP	J:37052
Biological Process	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	ISO	J:164563
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	IBA	J:265628