GO Annotations Graph

• Symbol: Pou4f1
• Name: POU domain, class 4, transcription factor 1
• ID: MGI:102525

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IGI	J:233585
Molecular Function	GO:0003677	DNA binding	IDA	J:93311
Molecular Function	GO:0003677	DNA binding	IDA	J:83805
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:239207
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:83805
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:83805
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:277851
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IGI	J:224739
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:139182
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:83805
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:160718
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IGI	J:224739
Molecular Function	GO:0051020	GTPase binding	IPI	J:233585
Molecular Function	GO:0005515	protein binding	IPI	J:30561
Molecular Function	GO:0005515	protein binding	IPI	J:239215
Molecular Function	GO:0005515	protein binding	IPI	J:93311
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:160718
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:119937
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:83805
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:224739
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:235271
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:239217
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:239205
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:16381
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	IDA	J:235271
Cellular Component	GO:0000785	chromatin	IDA	J:119937
Cellular Component	GO:0000785	chromatin	IDA	J:160718
Cellular Component	GO:0005737	cytoplasm	IDA	J:239205
Cellular Component	GO:0043005	neuron projection	IDA	J:154739
Cellular Component	GO:0005634	nucleus	IDA	J:175134
Cellular Component	GO:0005634	nucleus	IDA	J:239205
Cellular Component	GO:0005634	nucleus	IDA	J:277981
Cellular Component	GO:0005634	nucleus	IDA	J:224739
Cellular Component	GO:0005634	nucleus	IDA	J:120983
Cellular Component	GO:0005634	nucleus	IDA	J:83805
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:277851
Biological Process	GO:0021535	cell migration in hindbrain	IMP	J:37118
Biological Process	GO:0071345	cellular response to cytokine stimulus	IDA	J:239205
Biological Process	GO:0071392	cellular response to estradiol stimulus	IDA	J:239215
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:35877
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:35877
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:37118
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:37118
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:35877
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:37118
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:37118
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:35877
Biological Process	GO:0021986	habenula development	IMP	J:154739
Biological Process	GO:0021986	habenula development	IMP	J:154739
Biological Process	GO:0007507	heart development	IGI	J:261834
Biological Process	GO:0060384	innervation	IMP	J:154739
Biological Process	GO:0060384	innervation	IMP	J:154739
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	IMP	J:239207
Biological Process	GO:0007498	mesoderm development	IMP	J:154369
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:296156
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:224739
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:296160
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:261834
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:160718
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0043069	negative regulation of programmed cell death	IMP	J:239207
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:160656
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:224739
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:154369
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:154369
Biological Process	GO:0007399	nervous system development	IDA	J:83805
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:93311
Biological Process	GO:0030182	neuron differentiation	IMP	J:100128
Biological Process	GO:0048665	neuron fate specification	IMP	J:160718
Biological Process	GO:0048665	neuron fate specification	IMP	J:154369
Biological Process	GO:0001764	neuron migration	IMP	J:37118
Biological Process	GO:0031175	neuron projection development	IDA	J:37869
Biological Process	GO:0048935	peripheral nervous system neuron development	IMP	J:160656
Biological Process	GO:0048935	peripheral nervous system neuron development	IMP	J:154369
Biological Process	GO:0048935	peripheral nervous system neuron development	IMP	J:160718
Biological Process	GO:0048935	peripheral nervous system neuron development	IGI	J:174563
Biological Process	GO:0048934	peripheral nervous system neuron differentiation	IMP	J:35877
Biological Process	GO:0048934	peripheral nervous system neuron differentiation	IMP	J:37118
Biological Process	GO:0048934	peripheral nervous system neuron differentiation	IMP	J:37118
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:37869
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IGI	J:93311
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IMP	J:239205
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:277851
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139182
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:160656
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:224739
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:239217
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:233585
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:83805
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:154369
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	IDA	J:239215
Biological Process	GO:0051355	proprioception involved in equilibrioception	IMP	J:35877
Biological Process	GO:0051355	proprioception involved in equilibrioception	IMP	J:37118
Biological Process	GO:0051726	regulation of cell cycle	IGI	J:296160
Biological Process	GO:0051726	regulation of cell cycle	IGI	J:296156
Biological Process	GO:0051726	regulation of cell cycle	IGI	J:224739
Biological Process	GO:0051726	regulation of cell cycle	IMP	J:239207
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	IDA	J:239215
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:83805
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:154739
Biological Process	GO:0050767	regulation of neurogenesis	IMP	J:154369
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0048880	sensory system development	IMP	J:160718
Biological Process	GO:0001967	suckling behavior	IMP	J:35877
Biological Process	GO:0001967	suckling behavior	IMP	J:37118
Biological Process	GO:0021559	trigeminal nerve development	IMP	J:154369
Biological Process	GO:0003223	ventricular compact myocardium morphogenesis	IMP	J:139182