Tbx5 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Tbx5
T-box 5
MGI:102541

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:81154
Molecular Function	GO:0003677	DNA binding	IDA	J:71845
Molecular Function	GO:0003677	DNA binding	IDA	J:71818
Molecular Function	GO:0003677	DNA binding	IDA	J:89500
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:190765
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:187715
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:187715
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:187715
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:81154
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:89500
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:71818
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:71845
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:240078
Molecular Function	GO:0005515	protein binding	IPI	J:240078
Molecular Function	GO:0005515	protein binding	IPI	J:241786
Molecular Function	GO:0005515	protein binding	IPI	J:105332
Molecular Function	GO:0005515	protein binding	IPI	J:201868
Molecular Function	GO:0005515	protein binding	IPI	J:180125
Molecular Function	GO:0005515	protein binding	IPI	J:71845
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:190765
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:175199
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:175199
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:71845
Cellular Component	GO:0005634	nucleus	IDA	J:110101
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:161903
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:161903
Biological Process	GO:0003283	atrial septum development	IMP	J:145175
Biological Process	GO:0060413	atrial septum morphogenesis	IGI	J:187715
Biological Process	GO:0003167	atrioventricular bundle cell differentiation	IMP	J:92050
Biological Process	GO:0060928	atrioventricular node cell development	IMP	J:92050
Biological Process	GO:0060929	atrioventricular node cell fate commitment	IMP	J:92050
Biological Process	GO:0003181	atrioventricular valve morphogenesis	IGI	J:145175
Biological Process	GO:0086054	bundle of His cell to Purkinje myocyte communication by electrical coupling	IMP	J:190765
Biological Process	GO:0003166	bundle of His development	IMP	J:190765
Biological Process	GO:0003166	bundle of His development	IGI	J:122971
Biological Process	GO:0003218	cardiac left ventricle formation	IMP	J:152142
Biological Process	GO:0003218	cardiac left ventricle formation	IBA	J:265628
Biological Process	GO:0055007	cardiac muscle cell differentiation	IMP	J:145214
Biological Process	GO:0055007	cardiac muscle cell differentiation	IGI	J:167933
Biological Process	GO:0055007	cardiac muscle cell differentiation	IGI	J:167933
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:145175
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:145175
Biological Process	GO:0001708	cell fate specification	IBA	J:265628
Biological Process	GO:0007267	cell-cell signaling	ISO	J:164563
Biological Process	GO:0086019	cell-cell signaling involved in cardiac conduction	IGI	J:190765
Biological Process	GO:0035115	embryonic forelimb morphogenesis	ISO	J:164563
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:81154
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:71845
Biological Process	GO:0030326	embryonic limb morphogenesis	ISO	J:164563
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:105332
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:83258
Biological Process	GO:0003197	endocardial cushion development	IGI	J:145175
Biological Process	GO:0035136	forelimb morphogenesis	ISO	J:37424
Biological Process	GO:0035136	forelimb morphogenesis	ISO	J:37423
Biological Process	GO:0035136	forelimb morphogenesis	IMP	J:95804
Biological Process	GO:0007507	heart development	ISO	J:164563
Biological Process	GO:0007507	heart development	IMP	J:71845
Biological Process	GO:0007507	heart development	IMP	J:112887
Biological Process	GO:0007507	heart development	IMP	J:92050
Biological Process	GO:0007507	heart development	ISO	J:37423
Biological Process	GO:0007507	heart development	ISO	J:37424
Biological Process	GO:0030324	lung development	IMP	J:81141
Biological Process	GO:0002009	morphogenesis of an epithelium	IMP	J:81141
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	ISO	J:164563
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0007389	pattern specification process	IBA	J:265628
Biological Process	GO:0007389	pattern specification process	IMP	J:92050
Biological Process	GO:0060039	pericardium development	ISO	J:164563
Biological Process	GO:1903781	positive regulation of cardiac conduction	IMP	J:190765
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:145175
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IGI	J:145175
Biological Process	GO:0051891	positive regulation of cardioblast differentiation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:101739
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:71818
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:71845
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:81154
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:89500
Biological Process	GO:1903598	positive regulation of gap junction assembly	IMP	J:190765
Biological Process	GO:0072513	positive regulation of secondary heart field cardioblast proliferation	IMP	J:187715
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:190765
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:122971
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:105332
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:210667
Biological Process	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization	IGI	J:190765
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:112887
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0003163	sinoatrial node development	IMP	J:71845
Biological Process	GO:0006366	transcription by RNA polymerase II	IGI	J:122971
Biological Process	GO:0060290	transdifferentiation	ISO	J:155856
Biological Process	GO:0003229	ventricular cardiac muscle tissue development	IGI	J:145175
Biological Process	GO:0003281	ventricular septum development	IMP	J:152142

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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