GO Annotations Graph

• Symbol: Pou3f3
• Name: POU domain, class 3, transcription factor 3
• ID: MGI:102564

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:93149
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:48317
Molecular Function	GO:0071837	HMG box domain binding	IPI	J:175179
Molecular Function	GO:0005515	protein binding	IPI	J:153344
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:153344
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:132749
Cellular Component	GO:0005634	nucleus	ISO	J:48317
Biological Process	GO:0007420	brain development	IEA	J:72247
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	IGI	J:77999
Biological Process	GO:0048878	chemical homeostasis	IMP	J:121470
Biological Process	GO:0021869	forebrain ventricular zone progenitor cell division	IGI	J:77999
Biological Process	GO:0001822	kidney development	IMP	J:84756
Biological Process	GO:0001822	kidney development	IMP	J:121470
Biological Process	GO:0072218	metanephric ascending thin limb development	IMP	J:84756
Biological Process	GO:0072240	metanephric DCT cell differentiation	IMP	J:84756
Biological Process	GO:0072236	metanephric loop of Henle development	IMP	J:84756
Biological Process	GO:0072227	metanephric macula densa development	IMP	J:84756
Biological Process	GO:0072233	metanephric thick ascending limb development	IMP	J:84756
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:84756
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:153344
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:48317
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:84756
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:84756
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:48317
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:119653
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0071918	urea transmembrane transport	IMP	J:121470