GO Annotations Graph

• Symbol: Ptprf
• Name: protein tyrosine phosphatase receptor type F
• ID: MGI:102695

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:164563
Molecular Function	GO:0035373	chondroitin sulfate proteoglycan binding	IPI	J:177108
Molecular Function	GO:0008201	heparin binding	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0005158	insulin receptor binding	ISO	J:155856
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0042301	phosphate ion binding	ISO	J:155856
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	ISO	J:177108
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:164563
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	IDA	J:201692
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	ISO	J:155856
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:177108
Cellular Component	GO:0043005	neuron projection	IDA	J:133094
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IDA	J:177108
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0031345	negative regulation of cell projection organization	ISO	J:155856
Biological Process	GO:0001960	negative regulation of cytokine-mediated signaling pathway	ISO	J:155856
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	ISO	J:155856
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway	ISO	J:155856
Biological Process	GO:1900121	negative regulation of receptor binding	ISO	J:164563
Biological Process	GO:0007399	nervous system development	ISO	J:155856
Biological Process	GO:0031102	neuron projection regeneration	IMP	J:133094
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	ISO	J:164563
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	IBA	J:265628
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:155856
Biological Process	GO:0048679	regulation of axon regeneration	IMP	J:177108
Biological Process	GO:0010975	regulation of neuron projection development	IMP	J:177108
Biological Process	GO:0099175	regulation of postsynapse organization	ISO	J:155856
Biological Process	GO:0050803	regulation of synapse structure or activity	ISO	J:155856
Biological Process	GO:0099560	synaptic membrane adhesion	ISO	J:164563
Biological Process	GO:0099560	synaptic membrane adhesion	ISO	J:155856
Biological Process	GO:0099560	synaptic membrane adhesion	IBA	J:265628