GO Annotations Graph

• Symbol: Efnb1
• Name: ephrin B1
• ID: MGI:102708

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046875	ephrin receptor binding	ISO	J:164563
Molecular Function	GO:0046875	ephrin receptor binding	IBA	J:265628
Molecular Function	GO:0046875	ephrin receptor binding	IPI	J:88877
Molecular Function	GO:0046875	ephrin receptor binding	IPI	J:88877
Molecular Function	GO:0005515	protein binding	IPI	J:200342
Molecular Function	GO:0005515	protein binding	IPI	J:106994
Molecular Function	GO:0005515	protein binding	IPI	J:88877
Molecular Function	GO:0005515	protein binding	IPI	J:149817
Molecular Function	GO:0097027	ubiquitin-protein transferase activator activity	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:149817
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	IDA	J:54097
Cellular Component	GO:0005634	nucleus	IDA	J:149817
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4093335
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IMP	J:72721
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0009880	embryonic pattern specification	IMP	J:89008
Biological Process	GO:0048013	ephrin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007399	nervous system development	ISO	J:155856
Biological Process	GO:0001755	neural crest cell migration	IMP	J:89008
Biological Process	GO:0042102	positive regulation of T cell proliferation	IDA	J:95036
Biological Process	GO:0099054	presynapse assembly	ISO	J:155856
Biological Process	GO:2000785	regulation of autophagosome assembly	ISO	J:164563
Biological Process	GO:0031295	T cell costimulation	IDA	J:94701
Biological Process	GO:0042098	T cell proliferation	IDA	J:95036