Cav1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cav1
caveolin 1, caveolae protein
MGI:102709

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051117	ATPase binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:30626
Molecular Function	GO:0070320	inward rectifier potassium channel inhibitor activity	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	IDA	J:215922
Molecular Function	GO:0060090	molecular adaptor activity	IBA	J:265628
Molecular Function	GO:0050998	nitric-oxide synthase binding	ISO	J:155856
Molecular Function	GO:0050998	nitric-oxide synthase binding	ISO	J:164563
Molecular Function	GO:0050998	nitric-oxide synthase binding	IPI	J:215922
Molecular Function	GO:0016504	peptidase activator activity	IMP	J:120811
Molecular Function	GO:0005515	protein binding	IPI	J:277932
Molecular Function	GO:0005515	protein binding	IPI	J:113994
Molecular Function	GO:0005515	protein binding	IPI	J:180559
Molecular Function	GO:0005515	protein binding	IPI	J:187544
Molecular Function	GO:0005515	protein binding	IPI	J:269642
Molecular Function	GO:0005515	protein binding	IPI	J:159068
Molecular Function	GO:0005515	protein binding	IPI	J:282620
Molecular Function	GO:0005515	protein binding	IPI	J:116930
Molecular Function	GO:0005515	protein binding	IPI	J:230032
Molecular Function	GO:0005515	protein binding	IPI	J:126756
Molecular Function	GO:0005515	protein binding	IPI	J:122666
Molecular Function	GO:0005515	protein binding	IPI	J:78798
Molecular Function	GO:0005515	protein binding	IPI	J:182176
Molecular Function	GO:0005515	protein binding	IPI	J:104986
Molecular Function	GO:0005515	protein binding	IPI	J:122666
Molecular Function	GO:0005515	protein binding	IPI	J:176254
Molecular Function	GO:0046982	protein heterodimerization activity	IPI	J:217293
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IPI	J:215922
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IDA	J:215922
Molecular Function	GO:0033612	receptor serine/threonine kinase binding	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:0019905	syntaxin binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	IBA	J:265628
Cellular Component	GO:0002080	acrosomal membrane	IDA	J:73676
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0005901	caveola	IDA	J:30626
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0005901	caveola	IDA	J:75490
Cellular Component	GO:0005901	caveola	IDA	J:120010
Cellular Component	GO:0005901	caveola	IDA	J:75490
Cellular Component	GO:0005901	caveola	ISO	J:201740
Cellular Component	GO:0005901	caveola	ISO	J:73065
Cellular Component	GO:0005901	caveola	IDA	J:40432
Cellular Component	GO:0005901	caveola	IDA	J:37694
Cellular Component	GO:0005901	caveola	IDA	J:130715
Cellular Component	GO:0005901	caveola	IDA	J:129658
Cellular Component	GO:0005901	caveola	ISO	J:73065
Cellular Component	GO:0005901	caveola	TAS	J:55894
Cellular Component	GO:0002095	caveolar macromolecular signaling complex	IDA	J:75490
Cellular Component	GO:0005938	cell cortex	IDA	J:59358
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005929	cilium	IDA	J:73676
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:189648
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:120537
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	ISO	J:155856
Cellular Component	GO:0005925	focal adhesion	IDA	J:217289
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:120537
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0005811	lipid droplet	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:52977
Cellular Component	GO:0016020	membrane	IDA	J:167702
Cellular Component	GO:0016020	membrane	IDA	J:73676
Cellular Component	GO:0016020	membrane	IDA	J:116472
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	IDA	J:79453
Cellular Component	GO:0045121	membrane raft	IDA	J:85358
Cellular Component	GO:0045121	membrane raft	IDA	J:73676
Cellular Component	GO:0045121	membrane raft	IDA	J:120010
Cellular Component	GO:0045121	membrane raft	IDA	J:122666
Cellular Component	GO:0045121	membrane raft	IDA	J:54097
Cellular Component	GO:0045121	membrane raft	IDA	J:120537
Cellular Component	GO:0045121	membrane raft	IDA	J:79783
Cellular Component	GO:0045121	membrane raft	IDA	J:120010
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IBA	J:265628
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:30626
Cellular Component	GO:0005778	peroxisomal membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:91698
Cellular Component	GO:0005886	plasma membrane	IDA	J:30626
Cellular Component	GO:0005886	plasma membrane	IDA	J:79453
Cellular Component	GO:0005886	plasma membrane	IDA	J:116899
Cellular Component	GO:0005886	plasma membrane	IDA	J:75490
Cellular Component	GO:0005886	plasma membrane	IDA	J:79453
Cellular Component	GO:0005886	plasma membrane	IDA	J:120537
Cellular Component	GO:0005886	plasma membrane	IDA	J:120811
Cellular Component	GO:0005886	plasma membrane	IDA	J:86955
Cellular Component	GO:0005886	plasma membrane	IDA	J:186896
Cellular Component	GO:0005886	plasma membrane	IDA	J:116292
Cellular Component	GO:0005886	plasma membrane	IDA	J:116292
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	IDA	J:215922
Cellular Component	GO:0032991	protein-containing complex	IPI	J:122666
Cellular Component	GO:0032991	protein-containing complex	IPI	J:122666
Cellular Component	GO:0032991	protein-containing complex	IPI	J:122666
Cellular Component	GO:0032991	protein-containing complex	ISO	J:201740
Cellular Component	GO:0042383	sarcolemma	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IGI	J:109484
Biological Process	GO:0086098	angiotensin-activated signaling pathway involved in heart process	IGI	J:215922
Biological Process	GO:0097190	apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0071711	basement membrane organization	IMP	J:75490
Biological Process	GO:0055074	calcium ion homeostasis	IMP	J:82490
Biological Process	GO:0006816	calcium ion transport	IMP	J:122666
Biological Process	GO:0070836	caveola assembly	IGI	J:215923
Biological Process	GO:0070836	caveola assembly	ISO	J:164563
Biological Process	GO:0070836	caveola assembly	IBA	J:265628
Biological Process	GO:0070836	caveola assembly	IMP	J:109484
Biological Process	GO:0070836	caveola assembly	IDA	J:75490
Biological Process	GO:0072584	caveolin-mediated endocytosis	ISO	J:164563
Biological Process	GO:0072584	caveolin-mediated endocytosis	IMP	J:126756
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	IMP	J:119709
Biological Process	GO:0008283	cell population proliferation	IMP	J:119709
Biological Process	GO:0008283	cell population proliferation	IMP	J:82042
Biological Process	GO:0071360	cellular response to exogenous dsRNA	ISO	J:164563
Biological Process	GO:0071455	cellular response to hyperoxia	ISO	J:164563
Biological Process	GO:0071260	cellular response to mechanical stimulus	ISO	J:155856
Biological Process	GO:0071375	cellular response to peptide hormone stimulus	IGI	J:215922
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	IMP	J:176254
Biological Process	GO:0090398	cellular senescence	ISO	J:155856
Biological Process	GO:0033344	cholesterol efflux	ISO	J:155856
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:116292
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IMP	J:120010
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IMP	J:120010
Biological Process	GO:0006897	endocytosis	TAS	J:55894
Biological Process	GO:0001935	endothelial cell proliferation	IMP	J:75490
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:122666
Biological Process	GO:0048144	fibroblast proliferation	IMP	J:82042
Biological Process	GO:0002067	glandular epithelial cell differentiation	IMP	J:120010
Biological Process	GO:0038016	insulin receptor internalization	IMP	J:281214
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:155856
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:120603
Biological Process	GO:0033484	intracellular nitric oxide homeostasis	IMP	J:78603
Biological Process	GO:0007595	lactation	IMP	J:120010
Biological Process	GO:0019915	lipid storage	IMP	J:75490
Biological Process	GO:0019915	lipid storage	IMP	J:75490
Biological Process	GO:0032507	maintenance of protein location in cell	ISO	J:155856
Biological Process	GO:0030879	mammary gland development	IMP	J:120010
Biological Process	GO:0030879	mammary gland development	IMP	J:120010
Biological Process	GO:0030879	mammary gland development	IMP	J:120010
Biological Process	GO:0060056	mammary gland involution	IMP	J:120010
Biological Process	GO:0000165	MAPK cascade	IMP	J:120010
Biological Process	GO:0051899	membrane depolarization	IMP	J:120603
Biological Process	GO:0046785	microtubule polymerization	ISO	J:155856
Biological Process	GO:0046716	muscle cell cellular homeostasis	IMP	J:120603
Biological Process	GO:2000811	negative regulation of anoikis	IMP	J:187544
Biological Process	GO:2000811	negative regulation of anoikis	ISO	J:164563
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	ISO	J:164563
Biological Process	GO:1905949	negative regulation of calcium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IDA	J:163148
Biological Process	GO:2001258	negative regulation of cation channel activity	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:119709
Biological Process	GO:0001960	negative regulation of cytokine-mediated signaling pathway	IMP	J:120010
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	IBA	J:265628
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	IMP	J:75490
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IMP	J:120010
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IMP	J:120010
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	IMP	J:82042
Biological Process	GO:1903609	negative regulation of inward rectifier potassium channel activity	ISO	J:164563
Biological Process	GO:0043407	negative regulation of MAP kinase activity	IMP	J:120010
Biological Process	GO:0043409	negative regulation of MAPK cascade	IMP	J:120010
Biological Process	GO:0043409	negative regulation of MAPK cascade	IMP	J:82042
Biological Process	GO:0010656	negative regulation of muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0060546	negative regulation of necroptotic process	IMP	J:192110
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	IMP	J:82042
Biological Process	GO:0051001	negative regulation of nitric-oxide synthase activity	IMP	J:104734
Biological Process	GO:0051001	negative regulation of nitric-oxide synthase activity	IMP	J:144878
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation	IMP	J:215922
Biological Process	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation	ISO	J:164563
Biological Process	GO:0048550	negative regulation of pinocytosis	ISO	J:164563
Biological Process	GO:1901380	negative regulation of potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:164563
Biological Process	GO:0061099	negative regulation of protein tyrosine kinase activity	ISO	J:164563
Biological Process	GO:0061099	negative regulation of protein tyrosine kinase activity	IMP	J:215922
Biological Process	GO:0061099	negative regulation of protein tyrosine kinase activity	IBA	J:265628
Biological Process	GO:0031397	negative regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0031397	negative regulation of protein ubiquitination	IMP	J:187544
Biological Process	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	IDA	J:120010
Biological Process	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	IGI	J:120010
Biological Process	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	IMP	J:120010
Biological Process	GO:0009968	negative regulation of signal transduction	IDA	J:52621
Biological Process	GO:0014912	negative regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:163148
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	IMP	J:120010
Biological Process	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	IDA	J:120010
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0006809	nitric oxide biosynthetic process	IMP	J:82042
Biological Process	GO:0010524	positive regulation of calcium ion transport into cytosol	IDA	J:146324
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0043085	positive regulation of catalytic activity	IMP	J:120811
Biological Process	GO:0060355	positive regulation of cell adhesion molecule production	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:105133
Biological Process	GO:0045807	positive regulation of endocytosis	ISO	J:155856
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:1903598	positive regulation of gap junction assembly	IMP	J:215922
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:215922
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0031116	positive regulation of microtubule polymerization	ISO	J:155856
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:164563
Biological Process	GO:0031398	positive regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0009967	positive regulation of signal transduction	ISO	J:155856
Biological Process	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	ISO	J:164563
Biological Process	GO:0045907	positive regulation of vasoconstriction	ISO	J:155856
Biological Process	GO:0045907	positive regulation of vasoconstriction	IMP	J:75490
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	IMP	J:215922
Biological Process	GO:0008104	protein localization	IMP	J:122666
Biological Process	GO:0015031	protein transport	IMP	J:126756
Biological Process	GO:0031623	receptor internalization	ISO	J:164563
Biological Process	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0019065	receptor-mediated endocytosis of virus by host cell	ISO	J:164563
Biological Process	GO:0030193	regulation of blood coagulation	ISO	J:164563
Biological Process	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	IMP	J:215922
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	IBA	J:265628
Biological Process	GO:2000535	regulation of entry of bacterium into host cell	ISO	J:164563
Biological Process	GO:0019217	regulation of fatty acid metabolic process	IMP	J:75490
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	IMP	J:215922
Biological Process	GO:0098903	regulation of membrane repolarization during action potential	ISO	J:164563
Biological Process	GO:0052547	regulation of peptidase activity	IMP	J:120811
Biological Process	GO:1900027	regulation of ruffle assembly	ISO	J:164563
Biological Process	GO:0006940	regulation of smooth muscle contraction	IMP	J:120603
Biological Process	GO:0006940	regulation of smooth muscle contraction	IMP	J:116899
Biological Process	GO:0002026	regulation of the force of heart contraction	IMP	J:104734
Biological Process	GO:0003057	regulation of the force of heart contraction by chemical signal	IGI	J:144878
Biological Process	GO:0098911	regulation of ventricular cardiac muscle cell action potential	IMP	J:215922
Biological Process	GO:0009617	response to bacterium	ISO	J:164563
Biological Process	GO:0051592	response to calcium ion	IDA	J:146324
Biological Process	GO:0043627	response to estrogen	ISO	J:120010
Biological Process	GO:0043627	response to estrogen	IDA	J:120010
Biological Process	GO:0001666	response to hypoxia	IMP	J:122233
Biological Process	GO:0002931	response to ischemia	IMP	J:133702
Biological Process	GO:0009612	response to mechanical stimulus	ISO	J:155856
Biological Process	GO:0032570	response to progesterone	ISO	J:120010
Biological Process	GO:0007519	skeletal muscle tissue development	IMP	J:117199
Biological Process	GO:0031295	T cell costimulation	ISO	J:164563
Biological Process	GO:0006641	triglyceride metabolic process	IMP	J:75490
Biological Process	GO:0007260	tyrosine phosphorylation of STAT protein	IMP	J:120010
Biological Process	GO:0001570	vasculogenesis	IMP	J:122233
Biological Process	GO:0042310	vasoconstriction	IMP	J:120603
Biological Process	GO:0042060	wound healing	ISO	J:155856

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