GO Annotations Graph

• Symbol: Vav2
• Name: vav 2 oncogene
• ID: MGI:102718

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005154	epidermal growth factor receptor binding	IPI	J:100216
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IMP	J:100216
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:110334
Molecular Function	GO:0005515	protein binding	IPI	J:180687
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:100216
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-442289
Cellular Component	GO:0005886	plasma membrane	IDA	J:100216
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0016477	cell migration	IGI	J:100216
Biological Process	GO:0030031	cell projection assembly	IGI	J:100216
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0030032	lamellipodium assembly	IGI	J:100216
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	IGI	J:100216
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0043087	regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0007264	small GTPase mediated signal transduction	IMP	J:100216