GO Annotations Graph

• Symbol: Trim25
• Name: tripartite motif-containing 25
• ID: MGI:102749

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016874	ligase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:296112
Molecular Function	GO:0039552	RIG-I binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:69273
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:296112
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0002753	cytosolic pattern recognition receptor signaling pathway	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IDA	J:205675
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0046597	negative regulation of viral entry into host cell	IDA	J:205675
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0006513	protein monoubiquitination	ISO	J:164563
Biological Process	GO:0032880	regulation of protein localization	IMP	J:296112
Biological Process	GO:0046596	regulation of viral entry into host cell	ISO	J:164563
Biological Process	GO:0043627	response to estrogen	ISO	J:164563
Biological Process	GO:0044790	suppression of viral release by host	IDA	J:205675
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0019076	viral release from host cell	ISO	J:164563