GO Annotations Graph

• Symbol: Zbtb7b
• Name: zinc finger and BTB domain containing 7B
• ID: MGI:102755

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:35138
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:35138
Molecular Function	GO:0003677	DNA binding	IDA	J:20520
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:20520
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:35138
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	IMP	J:189792
Molecular Function	GO:0042826	histone deacetylase binding	IPI	J:189792
Molecular Function	GO:0042802	identical protein binding	IDA	J:35138
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:187647
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:244072
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:189792
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:20520
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:259304
Biological Process	GO:1990845	adaptive thermogenesis	IMP	J:244072
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007595	lactation	IMP	J:259304
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043377	negative regulation of CD8-positive, alpha-beta T cell differentiation	IMP	J:189792
Biological Process	GO:0043377	negative regulation of CD8-positive, alpha-beta T cell differentiation	IMP	J:258710
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:190936
Biological Process	GO:0051141	negative regulation of NK T cell proliferation	IMP	J:190672
Biological Process	GO:2000320	negative regulation of T-helper 17 cell differentiation	IMP	J:190936
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:189792
Biological Process	GO:0001865	NK T cell differentiation	IMP	J:190672
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	IMP	J:244072
Biological Process	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	IMP	J:258710
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:244072
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:258710
Biological Process	GO:0010628	positive regulation of gene expression	IBA	J:265628
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:170688
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	IMP	J:259304
Biological Process	GO:0032740	positive regulation of interleukin-17 production	IMP	J:190672
Biological Process	GO:2000640	positive regulation of SREBP signaling pathway	IMP	J:259304
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:20520
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:35138
Biological Process	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation	IMP	J:141145
Biological Process	GO:0010468	regulation of gene expression	IMP	J:190936
Biological Process	GO:0045622	regulation of T-helper cell differentiation	IMP	J:141145
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0032868	response to insulin	IMP	J:259304