Six3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Six3
sine oculis-related homeobox 3
MGI:102764

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:77680
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:116102
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:123470
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:81797
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:116102
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:116102
Molecular Function	GO:0042826	histone deacetylase binding	IPI	J:123470
Molecular Function	GO:0005515	protein binding	IPI	J:212800
Molecular Function	GO:0005515	protein binding	IPI	J:123470
Molecular Function	GO:0005515	protein binding	IPI	J:103131
Molecular Function	GO:0005515	protein binding	IPI	J:77680
Molecular Function	GO:0005515	protein binding	IPI	J:77680
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:116102
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:35368
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Molecular Function	GO:0001222	transcription corepressor binding	IPI	J:123470
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:103131
Cellular Component	GO:0005634	nucleus	IDA	J:35368
Cellular Component	GO:0005634	nucleus	IDA	J:77680
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Biological Process	GO:1902742	apoptotic process involved in development	IMP	J:140315
Biological Process	GO:0007420	brain development	IBA	J:265628
Biological Process	GO:0007420	brain development	IMP	J:81797
Biological Process	GO:0043010	camera-type eye development	IGI	J:77351
Biological Process	GO:0021846	cell proliferation in forebrain	IMP	J:140315
Biological Process	GO:0048512	circadian behavior	IMP	J:171421
Biological Process	GO:0021536	diencephalon development	IGI	J:130851
Biological Process	GO:0002070	epithelial cell maturation	IMP	J:178674
Biological Process	GO:0001654	eye development	ISO	J:164563
Biological Process	GO:0001654	eye development	IBA	J:265628
Biological Process	GO:0001654	eye development	IDA	J:77680
Biological Process	GO:0021797	forebrain anterior/posterior pattern specification	IMP	J:130851
Biological Process	GO:0021797	forebrain anterior/posterior pattern specification	IGI	J:130851
Biological Process	GO:0021798	forebrain dorsal/ventral pattern formation	ISO	J:164563
Biological Process	GO:0008406	gonad development	IGI	J:142425
Biological Process	GO:0002088	lens development in camera-type eye	IDA	J:67049
Biological Process	GO:1990086	lens fiber cell apoptotic process	IDA	J:77351
Biological Process	GO:0070306	lens fiber cell differentiation	IDA	J:77351
Biological Process	GO:0060235	lens induction in camera-type eye	IMP	J:116102
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0035264	multicellular organism growth	IGI	J:142425
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:67049
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:77680
Biological Process	GO:0045665	negative regulation of neuron differentiation	IDA	J:212804
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	IMP	J:81797
Biological Process	GO:0014016	neuroblast differentiation	IMP	J:178674
Biological Process	GO:0097402	neuroblast migration	IMP	J:178674
Biological Process	GO:0003404	optic vesicle morphogenesis	IDA	J:70282
Biological Process	GO:0021983	pituitary gland development	IMP	J:142425
Biological Process	GO:0021983	pituitary gland development	IGI	J:142425
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:116102
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:116102
Biological Process	GO:0006606	protein import into nucleus	IDA	J:103131
Biological Process	GO:0009946	proximal/distal axis specification	IDA	J:212815
Biological Process	GO:1901987	regulation of cell cycle phase transition	IDA	J:212804
Biological Process	GO:0042127	regulation of cell population proliferation	IMP	J:142425
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:2000177	regulation of neural precursor cell proliferation	IDA	J:212804
Biological Process	GO:0061074	regulation of neural retina development	IMP	J:165328
Biological Process	GO:1902692	regulation of neuroblast proliferation	IMP	J:178674
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0021537	telencephalon development	IMP	J:140315
Biological Process	GO:0021537	telencephalon development	IMP	J:130851
Biological Process	GO:0021978	telencephalon regionalization	IMP	J:140315
Biological Process	GO:0030878	thyroid gland development	IGI	J:142425

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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