GO Annotations Graph

• Symbol: Bdkrb2
• Name: bradykinin receptor, beta 2
• ID: MGI:102845

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031698	beta-2 adrenergic receptor binding	ISO	J:155856
Molecular Function	GO:0004947	bradykinin receptor activity	ISO	J:155856
Molecular Function	GO:0004947	bradykinin receptor activity	ISO	J:164563
Molecular Function	GO:0004947	bradykinin receptor activity	IBA	J:265628
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0031702	type 1 angiotensin receptor binding	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0002438	acute inflammatory response to antigenic stimulus	ISO	J:155856
Biological Process	GO:0050482	arachidonic acid secretion	ISO	J:164563
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:1990127	intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	IGI	J:111678
Biological Process	GO:1990127	intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	IGI	J:111678
Biological Process	GO:0035633	maintenance of blood-brain barrier	ISO	J:155856
Biological Process	GO:0045776	negative regulation of blood pressure	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	IMP	J:111678
Biological Process	GO:1902239	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	IGI	J:111678
Biological Process	GO:1902239	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	IGI	J:111678
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	IMP	J:111678
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0009651	response to salt stress	IGI	J:111678
Biological Process	GO:0009651	response to salt stress	IGI	J:111678
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0006939	smooth muscle contraction	IEA	J:72247
Biological Process	GO:0042310	vasoconstriction	IEA	J:72247
Biological Process	GO:0042311	vasodilation	ISO	J:164563
Biological Process	GO:0042311	vasodilation	IMP	J:115590