Scx GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Scx
scleraxis scleraxis bHLH transcription factor
MGI:102934

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	ISO	J:164563
Molecular Function	GO:0043425	bHLH transcription factor binding	IPI	J:177244
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:123002
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:24330
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0070888	E-box binding	IDA	J:177244
Molecular Function	GO:0070888	E-box binding	IDA	J:24330
Molecular Function	GO:0070888	E-box binding	IDA	J:156015
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:24330
Molecular Function	GO:0005515	protein binding	IPI	J:123002
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:24330
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:177178
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:177247
Cellular Component	GO:0005634	nucleus	IDA	J:177244
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:177244
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:156015
Biological Process	GO:0051216	cartilage development	NAS	J:177244
Biological Process	GO:0030154	cell differentiation	IMP	J:155292
Biological Process	GO:0071773	cellular response to BMP stimulus	IEP	J:177178
Biological Process	GO:0071260	cellular response to mechanical stimulus	IEP	J:177225
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	IEP	J:177178
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	IEP	J:136394
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:156015
Biological Process	GO:0030199	collagen fibril organization	IMP	J:155292
Biological Process	GO:0035993	deltoid tuberosity development	IMP	J:156015
Biological Process	GO:0035993	deltoid tuberosity development	IMP	J:122742
Biological Process	GO:0032502	developmental process	IBA	J:265628
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:177178
Biological Process	GO:0048706	embryonic skeletal system development	IEP	J:24330
Biological Process	GO:0001958	endochondral ossification	IMP	J:156015
Biological Process	GO:0060325	face morphogenesis	IEP	J:136394
Biological Process	GO:0003188	heart valve formation	IMP	J:155292
Biological Process	GO:0003179	heart valve morphogenesis	IMP	J:155292
Biological Process	GO:0001707	mesoderm formation	IMP	J:55991
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:55991
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:155292
Biological Process	GO:0061036	positive regulation of cartilage development	IMP	J:55991
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:55991
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	IDA	J:177247
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	IMP	J:155292
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:177244
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:24330
Biological Process	GO:2000543	positive regulation of gastrulation	IMP	J:55991
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:177244
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:155292
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:156015
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:177247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:24330
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:177247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:156015
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:123002
Biological Process	GO:0061035	regulation of cartilage development	IMP	J:155292
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0061056	sclerotome development	IEP	J:24330
Biological Process	GO:0035914	skeletal muscle cell differentiation	IMP	J:178918
Biological Process	GO:0035990	tendon cell differentiation	IMP	J:156015
Biological Process	GO:0035990	tendon cell differentiation	IMP	J:122742
Biological Process	GO:0035989	tendon development	IMP	J:122742
Biological Process	GO:0035992	tendon formation	IMP	J:86422
Biological Process	GO:0035992	tendon formation	IMP	J:122742
Biological Process	GO:0001894	tissue homeostasis	IMP	J:155292

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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