GO Annotations Graph

• Symbol: Cdk7
• Name: cyclin dependent kinase 7
• ID: MGI:102956

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	ISO	J:164563
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	ISO	J:155856
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	ISS	J:69035
Molecular Function	GO:0016301	kinase activity	IDA	J:69035
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:129766
Molecular Function	GO:0004672	protein kinase activity	IDA	J:83562
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	ISO	J:164563
Molecular Function	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0070516	CAK-ERCC2 complex	ISO	J:164563
Cellular Component	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:69035
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:101015
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0000439	transcription factor TFIIH core complex	ISO	J:164563
Cellular Component	GO:0005675	transcription factor TFIIH holo complex	ISO	J:164563
Cellular Component	GO:0005675	transcription factor TFIIH holo complex	ISO	J:155856
Cellular Component	GO:0070985	transcription factor TFIIK complex	ISO	J:164563
Cellular Component	GO:0070985	transcription factor TFIIK complex	IBA	J:265628
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	ISO	J:164563