GO Annotations Graph

• Symbol: E2f4
• Name: E2F transcription factor 4
• ID: MGI:103012

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:188795
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:94257
Molecular Function	GO:0003677	DNA binding	IDA	J:61792
Molecular Function	GO:0001216	DNA-binding transcription activator activity	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:94257
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:64193
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:1990841	promoter-specific chromatin binding	ISO	J:216069
Molecular Function	GO:0005515	protein binding	IPI	J:26103
Molecular Function	GO:0005515	protein binding	IPI	J:95187
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:63626
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:76061
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	TAS	J:64193
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8978954
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8978970
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8978980
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8978989
Cellular Component	GO:0005634	nucleus	IDA	J:94257
Cellular Component	GO:0005634	nucleus	IDA	J:61792
Cellular Component	GO:0005634	nucleus	IDA	J:121517
Cellular Component	GO:0005634	nucleus	TAS	J:64193
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IEA	J:72247
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:64192
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:64193
Biological Process	GO:0008015	blood circulation	IMP	J:64192
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0006884	cell volume homeostasis	IMP	J:64193
Biological Process	GO:0060271	cilium assembly	IMP	J:121517
Biological Process	GO:0002064	epithelial cell development	IMP	J:121517
Biological Process	GO:0000278	mitotic cell cycle	IEA	J:72247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:26103
Biological Process	GO:0051726	regulation of cell cycle	TAS	J:64192
Biological Process	GO:0042127	regulation of cell population proliferation	IDA	J:61792
Biological Process	GO:0008361	regulation of cell size	IMP	J:64193
Biological Process	GO:0006355	regulation of DNA-templated transcription	TAS	J:64193
Biological Process	GO:0006355	regulation of DNA-templated transcription	TAS	J:64192
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	IGI	J:94257
Biological Process	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	IDA	J:63626