GO Annotations Graph

• Symbol: Reln
• Name: reelin
• ID: MGI:103022

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0070325	lipoprotein particle receptor binding	IPI	J:180496
Molecular Function	GO:0070325	lipoprotein particle receptor binding	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:247409
Molecular Function	GO:0005515	protein binding	IPI	J:212819
Molecular Function	GO:0005515	protein binding	IPI	J:248288
Molecular Function	GO:0008236	serine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0070326	very-low-density lipoprotein particle receptor binding	IPI	J:180496
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:96577
Cellular Component	GO:0005737	cytoplasm	IDA	J:150768
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:96969
Cellular Component	GO:0031012	extracellular matrix	IDA	J:185190
Cellular Component	GO:0031012	extracellular matrix	TAS	J:75822
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IDA	J:107720
Cellular Component	GO:0005615	extracellular space	IDA	J:109819
Cellular Component	GO:0005615	extracellular space	IDA	J:83566
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0110157	reelin complex	ISO	J:164563
Biological Process	GO:0008306	associative learning	IMP	J:184736
Biological Process	GO:0008306	associative learning	IDA	J:184736
Biological Process	GO:0007411	axon guidance	IMP	J:104312
Biological Process	GO:0007420	brain development	ISO	J:155856
Biological Process	GO:0007420	brain development	IMP	J:79141
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0016477	cell migration	IMP	J:127421
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	IMP	J:84752
Biological Process	GO:0007417	central nervous system development	IMP	J:75822
Biological Process	GO:0021987	cerebral cortex development	IMP	J:174459
Biological Process	GO:0021800	cerebral cortex tangential migration	IMP	J:119267
Biological Process	GO:0016358	dendrite development	IMP	J:87427
Biological Process	GO:0016358	dendrite development	IGI	J:87427
Biological Process	GO:0021542	dentate gyrus development	ISO	J:155856
Biological Process	GO:0030900	forebrain development	IMP	J:127421
Biological Process	GO:0010001	glial cell differentiation	IMP	J:84752
Biological Process	GO:0021766	hippocampus development	IDA	J:128028
Biological Process	GO:1904936	interneuron migration	IMP	J:89993
Biological Process	GO:0097477	lateral motor column neuron migration	IMP	J:166792
Biological Process	GO:0021819	layer formation in cerebral cortex	IMP	J:183823
Biological Process	GO:0007612	learning	IMP	J:184736
Biological Process	GO:0007626	locomotory behavior	ISO	J:155856
Biological Process	GO:0007626	locomotory behavior	IMP	J:13038
Biological Process	GO:0007616	long-term memory	IMP	J:184736
Biological Process	GO:0007616	long-term memory	IDA	J:184736
Biological Process	GO:0060291	long-term synaptic potentiation	IMP	J:184736
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:142541
Biological Process	GO:0097475	motor neuron migration	IMP	J:97218
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0001764	neuron migration	ISO	J:155856
Biological Process	GO:0001764	neuron migration	IMP	J:83566
Biological Process	GO:0001764	neuron migration	IMP	J:79141
Biological Process	GO:0001764	neuron migration	IGI	J:67864
Biological Process	GO:0097114	NMDA glutamate receptor clustering	IMP	J:175650
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:109819
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:109819
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	IMP	J:128028
Biological Process	GO:2000969	positive regulation of AMPA receptor activity	IDA	J:128028
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	IMP	J:184736
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	IDA	J:184736
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	IMP	J:175650
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	IDA	J:184736
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	IMP	J:184736
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IMP	J:159385
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IMP	J:219074
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IMP	J:128028
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IDA	J:128028
Biological Process	GO:1902078	positive regulation of lateral motor column neuron migration	IMP	J:166792
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	IDA	J:184736
Biological Process	GO:0010976	positive regulation of neuron projection development	IMP	J:128028
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:184736
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:180496
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IDA	J:175650
Biological Process	GO:0045860	positive regulation of protein kinase activity	IGI	J:109819
Biological Process	GO:0045860	positive regulation of protein kinase activity	IDA	J:109819
Biological Process	GO:0045860	positive regulation of protein kinase activity	IGI	J:109819
Biological Process	GO:0045860	positive regulation of protein kinase activity	IGI	J:109819
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IDA	J:313948
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	IDA	J:184736
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	IMP	J:184736
Biological Process	GO:0051057	positive regulation of small GTPase mediated signal transduction	IDA	J:90089
Biological Process	GO:0090129	positive regulation of synapse maturation	IMP	J:128028
Biological Process	GO:0090129	positive regulation of synapse maturation	IDA	J:128028
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IMP	J:219074
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IMP	J:159385
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IDA	J:128028
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IMP	J:128028
Biological Process	GO:0032008	positive regulation of TOR signaling	IDA	J:175650
Biological Process	GO:0097107	postsynaptic density assembly	IC	J:175650
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	IMP	J:175650
Biological Process	GO:0035418	protein localization to synapse	IMP	J:175650
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0097120	receptor localization to synapse	IMP	J:175650
Biological Process	GO:0038026	reelin-mediated signaling pathway	IDA	J:180496
Biological Process	GO:0038026	reelin-mediated signaling pathway	IDA	J:184736
Biological Process	GO:0038026	reelin-mediated signaling pathway	NAS	J:313948
Biological Process	GO:0050795	regulation of behavior	IMP	J:159385
Biological Process	GO:0010468	regulation of gene expression	IMP	J:92350
Biological Process	GO:0045664	regulation of neuron differentiation	NAS	J:248393
Biological Process	GO:2001222	regulation of neuron migration	NAS	J:248393
Biological Process	GO:2000310	regulation of NMDA receptor activity	IMP	J:219074
Biological Process	GO:2000310	regulation of NMDA receptor activity	IMP	J:159385
Biological Process	GO:0060025	regulation of synaptic activity	NAS	J:248393
Biological Process	GO:0048265	response to pain	IMP	J:108959
Biological Process	GO:0021511	spinal cord patterning	IMP	J:108959
Biological Process	GO:0042403	thyroid hormone metabolic process	IMP	MGI:MGI:85368
Biological Process	GO:0021517	ventral spinal cord development	IEP	J:166792