GO Annotations Graph

• Symbol: Ecm1
• Name: extracellular matrix protein 1
• ID: MGI:103060

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0005134	interleukin-2 receptor binding	IPI	J:168252
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:159707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:26853
Cellular Component	GO:0005615	extracellular space	IDA	J:168252
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0031214	biomineral tissue development	IEA	J:60000
Biological Process	GO:0002063	chondrocyte development	IMP	J:159707
Biological Process	GO:0003416	endochondral bone growth	IMP	J:159707
Biological Process	GO:0006954	inflammatory response	IMP	J:168252
Biological Process	GO:0030502	negative regulation of bone mineralization	ISO	J:164563
Biological Process	GO:0001960	negative regulation of cytokine-mediated signaling pathway	IDA	J:168252
Biological Process	GO:0010466	negative regulation of peptidase activity	ISO	J:164563
Biological Process	GO:0001503	ossification	IEA	J:60000
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ISO	J:164563
Biological Process	GO:0030500	regulation of bone mineralization	IBA	J:265628
Biological Process	GO:0030500	regulation of bone mineralization	IMP	J:159707
Biological Process	GO:2000404	regulation of T cell migration	IMP	J:168252
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IMP	J:168252
Biological Process	GO:0002828	regulation of type 2 immune response	IMP	J:168252
Biological Process	GO:0007165	signal transduction	IEA	J:72247