Vdr GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Vdr
vitamin D (1,25-dihydroxyvitamin D3) receptor
MGI:103076

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1902098	calcitriol binding	ISO	J:155856
Molecular Function	GO:1902098	calcitriol binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:76833
Molecular Function	GO:0003677	DNA binding	IDA	J:95384
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:1902121	lithocholic acid binding	ISO	J:164563
Molecular Function	GO:0038186	lithocholic acid receptor activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:155856
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:94471
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	ISO	J:164563
Molecular Function	GO:0003676	nucleic acid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:236712
Molecular Function	GO:0005515	protein binding	IPI	J:196119
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:244975
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0036094	small molecule binding	ISO	J:164563
Molecular Function	GO:0005499	vitamin D binding	ISO	J:155856
Molecular Function	GO:0070644	vitamin D response element binding	ISO	J:164563
Molecular Function	GO:0070644	vitamin D response element binding	IBA	J:265628
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0001651	dense fibrillar component	ISO	J:155856
Cellular Component	GO:0000791	euchromatin	ISO	J:155856
Cellular Component	GO:0000792	heterochromatin	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016363	nuclear matrix	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:42054
Biological Process	GO:0060057	apoptotic process involved in mammary gland involution	IMP	J:92080
Biological Process	GO:0097190	apoptotic signaling pathway	ISO	J:155856
Biological Process	GO:0038183	bile acid signaling pathway	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	IMP	J:72578
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0000902	cell morphogenesis	ISO	J:164563
Biological Process	GO:0050892	intestinal absorption	IMP	J:72578
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:42054
Biological Process	GO:0007595	lactation	IMP	J:92080
Biological Process	GO:0060745	mammary gland branching involved in pregnancy	IMP	J:92080
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IMP	J:42054
Biological Process	GO:1900155	negative regulation of bone trabecula formation	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:76833
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0030279	negative regulation of ossification	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0035435	phosphate ion transmembrane transport	ISO	J:164563
Biological Process	GO:0060058	positive regulation of apoptotic process involved in mammary gland involution	IMP	J:92080
Biological Process	GO:0030501	positive regulation of bone mineralization	NAS	J:319681
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0045618	positive regulation of keratinocyte differentiation	ISO	J:164563
Biological Process	GO:2000830	positive regulation of parathyroid hormone secretion	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0010980	positive regulation of vitamin D 24-hydroxylase activity	ISO	J:164563
Biological Process	GO:0070564	positive regulation of vitamin D receptor signaling pathway	ISO	J:164563
Biological Process	GO:0060558	regulation of calcidiol 1-monooxygenase activity	IMP	J:43146
Biological Process	GO:0051924	regulation of calcium ion transport	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:94471
Biological Process	GO:1903412	response to bile acid	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:42054
Biological Process	GO:0070561	vitamin D receptor signaling pathway	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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