GO Annotations Graph

• Symbol: Pdpn
• Name: podoplanin
• ID: MGI:103098

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019956	chemokine binding	ISO	J:164563
Molecular Function	GO:0019956	chemokine binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:124651
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:164563
Molecular Function	GO:0051087	protein-folding chaperone binding	IBA	J:265628
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	IBA	J:265628
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0042995	cell projection	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:196984
Cellular Component	GO:0030175	filopodium	IDA	J:59380
Cellular Component	GO:0030175	filopodium	IBA	J:265628
Cellular Component	GO:0031527	filopodium membrane	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	IDA	J:59380
Cellular Component	GO:0030027	lamellipodium	IBA	J:265628
Cellular Component	GO:0031258	lamellipodium membrane	ISO	J:164563
Cellular Component	GO:0061851	leading edge of lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0031528	microvillus membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:217480
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:94978
Cellular Component	GO:0005886	plasma membrane	IDA	J:49356
Cellular Component	GO:0001726	ruffle	IDA	J:59380
Cellular Component	GO:0032587	ruffle membrane	ISO	J:164563
Cellular Component	GO:0097197	tetraspanin-enriched microdomain	ISO	J:164563
Biological Process	GO:0070252	actin-mediated cell contraction	IDA	J:217480
Biological Process	GO:0070252	actin-mediated cell contraction	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	ISO	J:73065
Biological Process	GO:0016477	cell migration	IMP	J:59380
Biological Process	GO:0008283	cell population proliferation	IMP	J:119680
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:119680
Biological Process	GO:0048286	lung alveolus development	IMP	J:119680
Biological Process	GO:0030324	lung development	IBA	J:265628
Biological Process	GO:0030324	lung development	IMP	J:82687
Biological Process	GO:0048535	lymph node development	IMP	J:222319
Biological Process	GO:0001946	lymphangiogenesis	IMP	J:94978
Biological Process	GO:0060838	lymphatic endothelial cell fate commitment	IMP	J:160267
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:222319
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:222319
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	IBA	J:265628
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:73065
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IBA	J:265628
Biological Process	GO:0090091	positive regulation of extracellular matrix disassembly	ISO	J:164563
Biological Process	GO:0090091	positive regulation of extracellular matrix disassembly	IBA	J:265628
Biological Process	GO:0010572	positive regulation of platelet activation	ISO	J:155856
Biological Process	GO:1901731	positive regulation of platelet aggregation	ISO	J:164563
Biological Process	GO:1901731	positive regulation of platelet aggregation	IDA	J:124651
Biological Process	GO:1901731	positive regulation of platelet aggregation	IMP	J:160267
Biological Process	GO:1901731	positive regulation of platelet aggregation	IBA	J:265628
Biological Process	GO:0006693	prostaglandin metabolic process	IMP	J:119680
Biological Process	GO:0030155	regulation of cell adhesion	IMP	J:222319
Biological Process	GO:0008360	regulation of cell shape	IEA	J:60000
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	IMP	J:119680
Biological Process	GO:2000392	regulation of lamellipodium morphogenesis	ISO	J:164563
Biological Process	GO:2000392	regulation of lamellipodium morphogenesis	IBA	J:265628
Biological Process	GO:1904328	regulation of myofibroblast contraction	IMP	J:222319
Biological Process	GO:1904328	regulation of myofibroblast contraction	IBA	J:265628
Biological Process	GO:1900024	regulation of substrate adhesion-dependent cell spreading	IMP	J:222319
Biological Process	GO:1900024	regulation of substrate adhesion-dependent cell spreading	IBA	J:265628
Biological Process	GO:0055093	response to hyperoxia	IBA	J:265628
Biological Process	GO:0007266	Rho protein signal transduction	ISO	J:164563
Biological Process	GO:0007266	Rho protein signal transduction	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IMP	J:119680
Biological Process	GO:0035239	tube morphogenesis	ISO	J:73065
Biological Process	GO:0061032	visceral serous pericardium development	TAS	J:169941
Biological Process	GO:0044319	wound healing, spreading of cells	ISO	J:164563