GO Annotations Graph

• Symbol: Gfi1
• Name: growth factor independent 1 transcription repressor
• ID: MGI:103170

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IBA	J:265628
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	IDA	J:175166
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:112647
Molecular Function	GO:0005515	protein binding	IPI	J:183969
Molecular Function	GO:0005515	protein binding	IPI	J:174998
Molecular Function	GO:0005515	protein binding	IPI	J:175175
Molecular Function	GO:0005515	protein binding	IPI	J:175118
Molecular Function	GO:0005515	protein binding	IPI	J:175166
Molecular Function	GO:0005515	protein binding	IPI	J:211358
Molecular Function	GO:0005515	protein binding	IPI	J:211358
Molecular Function	GO:0005515	protein binding	IPI	J:211358
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9634432
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:164563
Biological Process	GO:0045165	cell fate commitment	IMP	J:102106
Biological Process	GO:0001708	cell fate specification	IMP	J:102106
Biological Process	GO:0001708	cell fate specification	IMP	J:102106
Biological Process	GO:0001708	cell fate specification	IMP	J:102106
Biological Process	GO:0001708	cell fate specification	IMP	J:102106
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IEP	J:162780
Biological Process	GO:0030097	hemopoiesis	IEA	J:72247
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:80025
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:80025
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:80025
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:80025
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:80025
Biological Process	GO:0007638	mechanosensory behavior	IMP	J:80025
Biological Process	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity	ISO	J:164563
Biological Process	GO:0009996	negative regulation of cell fate specification	IMP	J:102106
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010977	negative regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	IMP	J:162780
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:162780
Biological Process	GO:0042660	positive regulation of cell fate specification	IMP	J:102106
Biological Process	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0051569	regulation of histone H3-K4 methylation	IEA	J:72247
Biological Process	GO:0034121	regulation of toll-like receptor signaling pathway	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628