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GO Annotations Graph
Symbol
Name
ID
Vegfa
vascular endothelial growth factor A
MGI:103178

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0042056chemoattractant activityISOJ:164563
Molecular FunctionGO:0042056chemoattractant activityIDAJ:174966
Molecular FunctionGO:0042056chemoattractant activityISOJ:164563
Molecular FunctionGO:0042056chemoattractant activityISOJ:155856
Molecular FunctionGO:0042056chemoattractant activityIBAJ:265628
Molecular FunctionGO:0005125cytokine activityISOJ:164563
Molecular FunctionGO:0001968fibronectin bindingISOJ:164563
Molecular FunctionGO:0008083growth factor activityISOJ:155856
Molecular FunctionGO:0008083growth factor activityISOJ:164563
Molecular FunctionGO:0008083growth factor activityIBAJ:265628
Molecular FunctionGO:0019838growth factor bindingISOJ:155856
Molecular FunctionGO:0008201heparin bindingISOJ:164563
Molecular FunctionGO:0042802identical protein bindingISOJ:155856
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0038191neuropilin bindingISOJ:164563
Molecular FunctionGO:0005161platelet-derived growth factor receptor bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:226761
Molecular FunctionGO:0048018receptor ligand activityISOJ:164563
Molecular FunctionGO:0048018receptor ligand activityISOJ:164563
Molecular FunctionGO:0043183vascular endothelial growth factor receptor 1 bindingISOJ:164563
Molecular FunctionGO:0043183vascular endothelial growth factor receptor 1 bindingIBAJ:265628
Molecular FunctionGO:0043184vascular endothelial growth factor receptor 2 bindingISOJ:155856
Molecular FunctionGO:0043184vascular endothelial growth factor receptor 2 bindingISOJ:164563
Molecular FunctionGO:0043184vascular endothelial growth factor receptor 2 bindingIBAJ:265628
Molecular FunctionGO:0005172vascular endothelial growth factor receptor bindingISOJ:164563
Molecular FunctionGO:0005172vascular endothelial growth factor receptor bindingISOJ:164563
Cellular ComponentGO:0005912adherens junctionISOJ:164563
Cellular ComponentGO:0005604basement membraneISOJ:155856
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:85570
Cellular ComponentGO:0005737cytoplasmIDAJ:191431
Cellular ComponentGO:0005615extracellular spaceHDAJ:221550
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0005615extracellular spaceIBAJ:265628
Cellular ComponentGO:0005615extracellular spaceIDAJ:210293
Cellular ComponentGO:0005615extracellular spaceIDAJ:138722
Cellular ComponentGO:0005615extracellular spaceIDAJ:145800
Cellular ComponentGO:0005615extracellular spaceIDAJ:145800
Cellular ComponentGO:0005615extracellular spaceIDAJ:125841
Cellular ComponentGO:0005615extracellular spaceIDAJ:223264
Cellular ComponentGO:0005615extracellular spaceIDAJ:77480
Cellular ComponentGO:0005615extracellular spaceIDAJ:204805
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0005634nucleusIDAJ:191431
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Cellular ComponentGO:0030141secretory granuleISOJ:164563
Cellular ComponentGO:1990150VEGF-A complexISOJ:164563
Cellular ComponentGO:0031982vesicleISOJ:155856
Biological ProcessGO:0032147activation of protein kinase activityISOJ:164563
Biological ProcessGO:0001525angiogenesisISOJ:155856
Biological ProcessGO:0001525angiogenesisISOJ:164563
Biological ProcessGO:0001525angiogenesisIMPJ:89363
Biological ProcessGO:0001525angiogenesisIDAJ:59160
Biological ProcessGO:0001525angiogenesisIDAJ:88338
Biological ProcessGO:0001525angiogenesisIMPJ:87618
Biological ProcessGO:0001525angiogenesisIMPJ:134823
Biological ProcessGO:0001525angiogenesisIDAJ:85570
Biological ProcessGO:0001525angiogenesisIMPJ:87618
Biological ProcessGO:0001525angiogenesisIMPJ:86673
Biological ProcessGO:0001525angiogenesisIGIJ:109722
Biological ProcessGO:0060978angiogenesis involved in coronary vascular morphogenesisISOJ:155856
Biological ProcessGO:0006915apoptotic processIMPJ:89363
Biological ProcessGO:0006915apoptotic processIMPJ:89363
Biological ProcessGO:0048844artery morphogenesisIMPJ:56003
Biological ProcessGO:0002575basophil chemotaxisISOJ:164563
Biological ProcessGO:0001568blood vessel developmentIMPJ:99650
Biological ProcessGO:0001568blood vessel developmentIMPJ:99650
Biological ProcessGO:0001568blood vessel developmentIMPJ:102398
Biological ProcessGO:0001568blood vessel developmentIMPJ:99650
Biological ProcessGO:0048514blood vessel morphogenesisIDAJ:100933
Biological ProcessGO:0048514blood vessel morphogenesisIGIJ:100933
Biological ProcessGO:0048514blood vessel morphogenesisIMPJ:100347
Biological ProcessGO:0001974blood vessel remodelingISOJ:155856
Biological ProcessGO:0060346bone trabecula formationIMPJ:191431
Biological ProcessGO:0061430bone trabecula morphogenesisIMPJ:191431
Biological ProcessGO:0001569branching involved in blood vessel morphogenesisISOJ:164563
Biological ProcessGO:0048593camera-type eye morphogenesisIMPJ:102398
Biological ProcessGO:0055013cardiac muscle cell developmentIMPJ:56003
Biological ProcessGO:0060948cardiac vascular smooth muscle cell developmentIMPJ:161912
Biological ProcessGO:0060326cell chemotaxisISOJ:155856
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0016477cell migrationIGIJ:95386
Biological ProcessGO:0016477cell migrationIGIJ:95386
Biological ProcessGO:0016477cell migrationIDAJ:95386
Biological ProcessGO:0002042cell migration involved in sprouting angiogenesisISOJ:164563
Biological ProcessGO:0008283cell population proliferationIMPJ:87618
Biological ProcessGO:0008283cell population proliferationIMPJ:87618
Biological ProcessGO:0098609cell-cell adhesionIGIJ:211130
Biological ProcessGO:0098609cell-cell adhesionIGIJ:211130
Biological ProcessGO:0071456cellular response to hypoxiaISOJ:58706
Biological ProcessGO:0071456cellular response to hypoxiaISOJ:58706
Biological ProcessGO:0035924cellular response to vascular endothelial growth factor stimulusISOJ:164563
Biological ProcessGO:0035924cellular response to vascular endothelial growth factor stimulusIGIJ:208348
Biological ProcessGO:0097533cellular stress response to acid chemicalISOJ:164563
Biological ProcessGO:0071679commissural neuron axon guidanceIDAJ:174966
Biological ProcessGO:0071679commissural neuron axon guidanceIMPJ:174966
Biological ProcessGO:0060982coronary artery morphogenesisIMPJ:161912
Biological ProcessGO:0003169coronary vein morphogenesisIMPJ:161912
Biological ProcessGO:0071542dopaminergic neuron differentiationIGIJ:117302
Biological ProcessGO:0035767endothelial cell chemotaxisISOJ:164563
Biological ProcessGO:0043542endothelial cell migrationIMPJ:209508
Biological ProcessGO:0001935endothelial cell proliferationIDAJ:285234
Biological ProcessGO:0030855epithelial cell differentiationIMPJ:102398
Biological ProcessGO:0002070epithelial cell maturationIMPJ:77480
Biological ProcessGO:0050673epithelial cell proliferationIMPJ:99650
Biological ProcessGO:0042462eye photoreceptor cell developmentIMPJ:102398
Biological ProcessGO:0003007heart morphogenesisIMPJ:56003
Biological ProcessGO:0048873homeostasis of number of cells within a tissueIMPJ:191431
Biological ProcessGO:0001701in utero embryonic developmentIMPJ:56003
Biological ProcessGO:0050930induction of positive chemotaxisISOJ:164563
Biological ProcessGO:0050930induction of positive chemotaxisIBAJ:265628
Biological ProcessGO:0001822kidney developmentIMPJ:56003
Biological ProcessGO:0007595lactationIMPJ:134823
Biological ProcessGO:0048286lung alveolus developmentISOJ:155856
Biological ProcessGO:0030324lung developmentIMPJ:77480
Biological ProcessGO:0030324lung developmentIMPJ:99650
Biological ProcessGO:0030324lung developmentIMPJ:99650
Biological ProcessGO:0060426lung vasculature developmentIMPJ:67327
Biological ProcessGO:0036303lymph vessel morphogenesisIMPJ:161912
Biological ProcessGO:0001946lymphangiogenesisIDAJ:158639
Biological ProcessGO:0001946lymphangiogenesisIGIJ:149253
Biological ProcessGO:0001946lymphangiogenesisIGIJ:149253
Biological ProcessGO:0030225macrophage differentiationISOJ:164563
Biological ProcessGO:0060749mammary gland alveolus developmentIMPJ:134823
Biological ProcessGO:0007498mesoderm developmentIMPJ:86673
Biological ProcessGO:0030224monocyte differentiationISOJ:164563
Biological ProcessGO:0097475motor neuron migrationIMPJ:226761
Biological ProcessGO:0048255mRNA stabilizationISOJ:155856
Biological ProcessGO:0007275multicellular organism developmentIEAJ:60000
Biological ProcessGO:1903392negative regulation of adherens junction organizationISOJ:164563
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:164563
Biological ProcessGO:0043066negative regulation of apoptotic processIMPJ:89363
Biological ProcessGO:1905604negative regulation of blood-brain barrier permeabilityISOJ:164563
Biological ProcessGO:0045779negative regulation of bone resorptionISOJ:155856
Biological ProcessGO:0022408negative regulation of cell-cell adhesionIGIJ:211130
Biological ProcessGO:0022408negative regulation of cell-cell adhesionIGIJ:211130
Biological ProcessGO:2000048negative regulation of cell-cell adhesion mediated by cadherinISOJ:164563
Biological ProcessGO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic processISOJ:164563
Biological ProcessGO:0010719negative regulation of epithelial to mesenchymal transitionIMPJ:199300
Biological ProcessGO:1903141negative regulation of establishment of endothelial barrierISOJ:164563
Biological ProcessGO:2001237negative regulation of extrinsic apoptotic signaling pathwayIDAJ:175836
Biological ProcessGO:0045599negative regulation of fat cell differentiationIMPJ:191431
Biological ProcessGO:0010629negative regulation of gene expressionISOJ:164563
Biological ProcessGO:0010629negative regulation of gene expressionISOJ:164563
Biological ProcessGO:0010629negative regulation of gene expressionIMPJ:191431
Biological ProcessGO:0043524negative regulation of neuron apoptotic processIDAJ:175836
Biological ProcessGO:1901215negative regulation of neuron deathISOJ:155856
Biological ProcessGO:0043069negative regulation of programmed cell deathISOJ:155856
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIISOJ:164563
Biological ProcessGO:0007399nervous system developmentISOJ:155856
Biological ProcessGO:0007405neuroblast proliferationIGIJ:117302
Biological ProcessGO:0048666neuron developmentIMPJ:175836
Biological ProcessGO:0003151outflow tract morphogenesisIMPJ:161912
Biological ProcessGO:0001541ovarian follicle developmentIMPJ:121170
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationIDAJ:204805
Biological ProcessGO:0050918positive chemotaxisIDAJ:174966
Biological ProcessGO:0050918positive chemotaxisISOJ:164563
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:164563
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:155856
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:164563
Biological ProcessGO:0045766positive regulation of angiogenesisIBAJ:265628
Biological ProcessGO:0045766positive regulation of angiogenesisIDAJ:158639
Biological ProcessGO:0048842positive regulation of axon extension involved in axon guidanceIDAJ:174966
Biological ProcessGO:0048842positive regulation of axon extension involved in axon guidanceIMPJ:174966
Biological ProcessGO:0043536positive regulation of blood vessel endothelial cell migrationISOJ:164563
Biological ProcessGO:1903589positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesisISOJ:164563
Biological ProcessGO:0090190positive regulation of branching involved in ureteric bud morphogenesisIDAJ:104351
Biological ProcessGO:0045785positive regulation of cell adhesionISOJ:164563
Biological ProcessGO:0051781positive regulation of cell divisionIEAJ:60000
Biological ProcessGO:0030335positive regulation of cell migrationISOJ:164563
Biological ProcessGO:0038089positive regulation of cell migration by vascular endothelial growth factor signaling pathwayISOJ:164563
Biological ProcessGO:0090050positive regulation of cell migration involved in sprouting angiogenesisISOJ:164563
Biological ProcessGO:0008284positive regulation of cell population proliferationISOJ:164563
Biological ProcessGO:0008284positive regulation of cell population proliferationISOJ:155856
Biological ProcessGO:0008284positive regulation of cell population proliferationIDAJ:125841
Biological ProcessGO:0038091positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0120162positive regulation of cold-induced thermogenesisIMPJ:249903
Biological ProcessGO:0032793positive regulation of CREB transcription factor activityISOJ:164563
Biological ProcessGO:2000573positive regulation of DNA biosynthetic processISOJ:164563
Biological ProcessGO:0038033positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0010595positive regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0010595positive regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationIBAJ:265628
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationISOJ:83025
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationIMPJ:99650
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationIMPJ:99650
Biological ProcessGO:1905278positive regulation of epithelial tube formationISOJ:164563
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeIDAJ:175836
Biological ProcessGO:0051894positive regulation of focal adhesion assemblyISOJ:164563
Biological ProcessGO:0010628positive regulation of gene expressionISOJ:164563
Biological ProcessGO:0010628positive regulation of gene expressionISOJ:164563
Biological ProcessGO:1901727positive regulation of histone deacetylase activityISOJ:164563
Biological ProcessGO:1901492positive regulation of lymphangiogenesisIDAJ:158639
Biological ProcessGO:0043406positive regulation of MAP kinase activityISOJ:164563
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:164563
Biological ProcessGO:0060754positive regulation of mast cell chemotaxisISOJ:164563
Biological ProcessGO:0060754positive regulation of mast cell chemotaxisIBAJ:265628
Biological ProcessGO:0002052positive regulation of neuroblast proliferationIGIJ:117302
Biological ProcessGO:0045669positive regulation of osteoblast differentiationIMPJ:191431
Biological ProcessGO:1900745positive regulation of p38MAPK cascadeISOJ:164563
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:1900086positive regulation of peptidyl-tyrosine autophosphorylationISOJ:164563
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationIDAJ:204805
Biological ProcessGO:0014068positive regulation of phosphatidylinositol 3-kinase signalingISOJ:164563
Biological ProcessGO:0042327positive regulation of phosphorylationISOJ:164563
Biological ProcessGO:0050927positive regulation of positive chemotaxisISOJ:164563
Biological ProcessGO:0031954positive regulation of protein autophosphorylationISOJ:164563
Biological ProcessGO:0031954positive regulation of protein autophosphorylationISOJ:164563
Biological ProcessGO:0051897positive regulation of protein kinase B signalingIDAJ:175836
Biological ProcessGO:0051897positive regulation of protein kinase B signalingISOJ:164563
Biological ProcessGO:0090037positive regulation of protein kinase C signalingISOJ:164563
Biological ProcessGO:1903572positive regulation of protein kinase D signalingISOJ:164563
Biological ProcessGO:1902966positive regulation of protein localization to early endosomeISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationIBAJ:265628
Biological ProcessGO:0031334positive regulation of protein-containing complex assemblyISOJ:164563
Biological ProcessGO:0002092positive regulation of receptor internalizationISOJ:164563
Biological ProcessGO:1902336positive regulation of retinal ganglion cell axon guidanceIMPJ:174966
Biological ProcessGO:0009967positive regulation of signal transductionISOJ:155856
Biological ProcessGO:0048661positive regulation of smooth muscle cell proliferationISOJ:155856
Biological ProcessGO:1903672positive regulation of sprouting angiogenesisISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIISOJ:155856
Biological ProcessGO:0061419positive regulation of transcription from RNA polymerase II promoter in response to hypoxiaISOJ:164563
Biological ProcessGO:1901165positive regulation of trophoblast cell migrationISOJ:164563
Biological ProcessGO:1900748positive regulation of vascular endothelial growth factor signaling pathwayISOJ:164563
Biological ProcessGO:0043117positive regulation of vascular permeabilityISOJ:164563
Biological ProcessGO:0043117positive regulation of vascular permeabilityISOJ:164563
Biological ProcessGO:0043117positive regulation of vascular permeabilityISOJ:155856
Biological ProcessGO:0043117positive regulation of vascular permeabilityIDAJ:59160
Biological ProcessGO:0043117positive regulation of vascular permeabilityIDAJ:209508
Biological ProcessGO:0031077post-embryonic camera-type eye developmentIMPJ:56003
Biological ProcessGO:0060319primitive erythrocyte differentiationIMPJ:96898
Biological ProcessGO:0008360regulation of cell shapeISOJ:164563
Biological ProcessGO:0045601regulation of endothelial cell differentiationIDAJ:204805
Biological ProcessGO:0040008regulation of growthIMPJ:56003
Biological ProcessGO:1901532regulation of hematopoietic progenitor cell differentiationIDAJ:204805
Biological ProcessGO:0010749regulation of nitric oxide mediated signal transductionISOJ:101420
Biological ProcessGO:0090259regulation of retinal ganglion cell axon guidanceIDAJ:174966
Biological ProcessGO:0090259regulation of retinal ganglion cell axon guidanceIMPJ:174966
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIISOJ:164563
Biological ProcessGO:0001666response to hypoxiaISOJ:155856
Biological ProcessGO:0001666response to hypoxiaISOJ:164563
Biological ProcessGO:0001666response to hypoxiaIBAJ:265628
Biological ProcessGO:0002040sprouting angiogenesisIDAJ:208348
Biological ProcessGO:0002040sprouting angiogenesisIBAJ:265628
Biological ProcessGO:0043129surfactant homeostasisIMPJ:77480
Biological ProcessGO:0042088T-helper 1 type immune responseISOJ:155856
Biological ProcessGO:0035148tube formationISOJ:164563
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:155856
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayISOJ:164563
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayIBAJ:265628
Biological ProcessGO:0036324vascular endothelial growth factor receptor-2 signaling pathwayISOJ:164563
Biological ProcessGO:0038084vascular endothelial growth factor signaling pathwayISOJ:164563
Biological ProcessGO:0038084vascular endothelial growth factor signaling pathwayIDAJ:175836
Biological ProcessGO:0038084vascular endothelial growth factor signaling pathwayISOJ:164563
Biological ProcessGO:0038084vascular endothelial growth factor signaling pathwayIBAJ:265628
Biological ProcessGO:0061042vascular wound healingISOJ:164563
Biological ProcessGO:0001944vasculature developmentIMPJ:56003
Biological ProcessGO:0042311vasodilationIDAJ:285234
Biological ProcessGO:0042311vasodilationIDAJ:285234
Biological ProcessGO:0038190VEGF-activated neuropilin signaling pathwayISOJ:164563
Biological ProcessGO:0038190VEGF-activated neuropilin signaling pathwayIMPJ:174966

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory