GO Annotations Graph

• Symbol: Nqo1
• Name: NAD(P)H dehydrogenase, quinone 1
• ID: MGI:103187

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	ISO	J:155856
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	IBA	J:265628
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	IDA	J:93514
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	IDA	J:441
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	IDA	J:101558
Molecular Function	GO:0050136	NADH dehydrogenase (quinone) activity	ISO	J:164563
Molecular Function	GO:0050136	NADH dehydrogenase (quinone) activity	ISO	J:155856
Molecular Function	GO:0050136	NADH dehydrogenase (quinone) activity	IDA	J:38455
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:265840
Molecular Function	GO:0005515	protein binding	IPI	J:265840
Molecular Function	GO:0004784	superoxide dismutase activity	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:265840
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:265840
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:155856
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0001816	cytokine production	IMP	J:265840
Biological Process	GO:0045087	innate immune response	IMP	J:265840
Biological Process	GO:0006116	NADH oxidation	ISO	J:155856
Biological Process	GO:0070995	NADPH oxidation	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043086	negative regulation of catalytic activity	IDA	J:63632
Biological Process	GO:0042177	negative regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0030163	protein catabolic process	IDA	J:265840
Biological Process	GO:0000209	protein polyubiquitination	IDA	J:265840
Biological Process	GO:0019430	removal of superoxide radicals	ISO	J:164563
Biological Process	GO:0014075	response to amine	ISO	J:155856
Biological Process	GO:1904844	response to L-glutamine	ISO	J:155856
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:265840
Biological Process	GO:0006979	response to oxidative stress	IMP	J:93514
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0006801	superoxide metabolic process	ISO	J:155856
Biological Process	GO:0006743	ubiquinone metabolic process	ISO	J:164563
Biological Process	GO:0042360	vitamin E metabolic process	ISO	J:164563
Biological Process	GO:0042373	vitamin K metabolic process	ISO	J:164563
Biological Process	GO:0042373	vitamin K metabolic process	ISO	J:155856
Biological Process	GO:0042373	vitamin K metabolic process	IDA	J:38455