GO Annotations Graph

• Symbol: Aqp1
• Name: aquaporin 1
• ID: MGI:103201

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008519	ammonium transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0008519	ammonium transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0035379	carbon dioxide transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0035379	carbon dioxide transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015267	channel activity	IEA	J:72247
Molecular Function	GO:0046875	ephrin receptor binding	IPI	J:62565
Molecular Function	GO:0015168	glycerol transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015168	glycerol transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015168	glycerol transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005223	intracellular cGMP-activated cation channel activity	ISO	J:164563
Molecular Function	GO:0030184	nitric oxide transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005267	potassium channel activity	ISO	J:164563
Molecular Function	GO:0015079	potassium ion transmembrane transporter activity	IDA	J:161102
Molecular Function	GO:0022857	transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015250	water channel activity	ISO	J:164563
Molecular Function	GO:0015250	water channel activity	ISO	J:155856
Molecular Function	GO:0015250	water channel activity	IBA	J:265628
Molecular Function	GO:0015250	water channel activity	TAS	J:65472
Molecular Function	GO:0005372	water transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005372	water transmembrane transporter activity	IDA	J:60202
Cellular Component	GO:0045177	apical part of cell	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:233568
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:102995
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:176751
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:149696
Cellular Component	GO:0030424	axon	IDA	J:123606
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0009925	basal plasma membrane	IDA	J:233568
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:102995
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0005903	brush border	ISO	J:155856
Cellular Component	GO:0005903	brush border	ISO	J:164563
Cellular Component	GO:0005903	brush border	IDA	J:102995
Cellular Component	GO:0031526	brush border membrane	ISO	J:164563
Cellular Component	GO:0005901	caveola	IDA	J:233568
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0032127	dense core granule membrane	ISO	J:73065
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0070062	extracellular exosome	IDA	J:154189
Cellular Component	GO:0016020	membrane	IDA	J:78895
Cellular Component	GO:0016020	membrane	IDA	J:99640
Cellular Component	GO:0016020	membrane	IDA	J:138417
Cellular Component	GO:0016020	membrane	IDA	J:99640
Cellular Component	GO:0016020	membrane	IDA	J:138417
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0032809	neuronal cell body membrane	ISO	J:155856
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:136507
Cellular Component	GO:0005886	plasma membrane	TAS	J:65472
Cellular Component	GO:0005886	plasma membrane	IDA	J:123606
Cellular Component	GO:0005886	plasma membrane	IDA	J:76855
Cellular Component	GO:0005886	plasma membrane	IDA	J:79279
Cellular Component	GO:0005886	plasma membrane	IDA	J:120884
Cellular Component	GO:0005886	plasma membrane	IDA	J:105693
Cellular Component	GO:0005886	plasma membrane	IDA	J:136507
Cellular Component	GO:0042383	sarcolemma	ISO	J:164563
Biological Process	GO:0072488	ammonium transmembrane transport	ISO	J:164563
Biological Process	GO:0048593	camera-type eye morphogenesis	IMP	J:76855
Biological Process	GO:0035378	carbon dioxide transmembrane transport	ISO	J:164563
Biological Process	GO:0035378	carbon dioxide transmembrane transport	IBA	J:265628
Biological Process	GO:0015670	carbon dioxide transport	ISO	J:164563
Biological Process	GO:0016477	cell migration	IMP	J:151020
Biological Process	GO:0006884	cell volume homeostasis	ISO	J:164563
Biological Process	GO:0019725	cellular homeostasis	ISO	J:164563
Biological Process	GO:0071474	cellular hyperosmotic response	ISO	J:164563
Biological Process	GO:0071320	cellular response to cAMP	ISO	J:164563
Biological Process	GO:0071280	cellular response to copper ion	ISO	J:164563
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	ISO	J:164563
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:164563
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:164563
Biological Process	GO:0071241	cellular response to inorganic substance	ISO	J:164563
Biological Process	GO:0071260	cellular response to mechanical stimulus	ISO	J:164563
Biological Process	GO:0071288	cellular response to mercury ion	ISO	J:164563
Biological Process	GO:0071732	cellular response to nitric oxide	ISO	J:164563
Biological Process	GO:0071300	cellular response to retinoic acid	ISO	J:164563
Biological Process	GO:0071472	cellular response to salt stress	ISO	J:164563
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0019934	cGMP-mediated signaling	ISO	J:164563
Biological Process	GO:0051458	corticotropin secretion	IMP	J:138417
Biological Process	GO:0050829	defense response to Gram-negative bacterium	IMP	J:161102
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:106259
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:106259
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:66829
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:79279
Biological Process	GO:0030950	establishment or maintenance of actin cytoskeleton polarity	ISO	J:164563
Biological Process	GO:0010761	fibroblast migration	IMP	J:151020
Biological Process	GO:0003094	glomerular filtration	IMP	J:102066
Biological Process	GO:0015793	glycerol transmembrane transport	ISO	J:164563
Biological Process	GO:0015793	glycerol transmembrane transport	ISO	J:155856
Biological Process	GO:0006972	hyperosmotic response	IBA	J:265628
Biological Process	GO:0009992	intracellular water homeostasis	ISO	J:164563
Biological Process	GO:0021670	lateral ventricle development	IEP	J:102995
Biological Process	GO:0044241	lipid digestion	IMP	J:68350
Biological Process	GO:0072220	metanephric descending thin limb development	IEP	J:138858
Biological Process	GO:0072239	metanephric glomerulus vasculature development	IEP	J:138858
Biological Process	GO:0072232	metanephric proximal convoluted tubule segment 2 development	IEP	J:138858
Biological Process	GO:0072230	metanephric proximal straight tubule development	IEP	J:138858
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	IMP	J:105929
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0030185	nitric oxide transport	ISO	J:164563
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0010634	positive regulation of epithelial cell migration	ISO	J:155856
Biological Process	GO:0010763	positive regulation of fibroblast migration	IMP	J:151020
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:164563
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ISO	J:155856
Biological Process	GO:0046878	positive regulation of saliva secretion	ISO	J:164563
Biological Process	GO:0006813	potassium ion transport	IDA	J:161102
Biological Process	GO:0070295	renal water absorption	IMP	J:110649
Biological Process	GO:0070295	renal water absorption	IMP	J:62449
Biological Process	GO:0070295	renal water absorption	IMP	J:118975
Biological Process	GO:0070295	renal water absorption	IMP	J:60362
Biological Process	GO:0070295	renal water absorption	IGI	J:60362
Biological Process	GO:0070295	renal water absorption	IGI	J:66829
Biological Process	GO:0070295	renal water absorption	IMP	J:79279
Biological Process	GO:0070295	renal water absorption	IMP	J:66829
Biological Process	GO:0070295	renal water absorption	IMP	J:61250
Biological Process	GO:0070295	renal water absorption	IMP	J:45888
Biological Process	GO:0070295	renal water absorption	IGI	J:102454
Biological Process	GO:0003097	renal water transport	ISO	J:164563
Biological Process	GO:0003097	renal water transport	IBA	J:265628
Biological Process	GO:0032940	secretion by cell	IMP	J:138417
Biological Process	GO:0033363	secretory granule organization	IMP	J:138417
Biological Process	GO:0019233	sensory perception of pain	IMP	J:105864
Biological Process	GO:0035377	transepithelial water transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0006833	water transport	ISO	J:155856
Biological Process	GO:0006833	water transport	ISO	J:164563
Biological Process	GO:0006833	water transport	IMP	J:52454
Biological Process	GO:0006833	water transport	IGI	J:79279
Biological Process	GO:0006833	water transport	IMP	J:66829
Biological Process	GO:0006833	water transport	IDA	J:60202
Biological Process	GO:0006833	water transport	IMP	J:124839
Biological Process	GO:0006833	water transport	IMP	J:133988
Biological Process	GO:0006833	water transport	IMP	J:114230
Biological Process	GO:0006833	water transport	IMP	J:104681
Biological Process	GO:0006833	water transport	IMP	J:106259
Biological Process	GO:0006833	water transport	IMP	J:53078
Biological Process	GO:0006833	water transport	IMP	J:116280
Biological Process	GO:0006833	water transport	IMP	J:106259
Biological Process	GO:0006833	water transport	IMP	J:136507
Biological Process	GO:0006833	water transport	IMP	J:105693
Biological Process	GO:0006833	water transport	IMP	J:105814
Biological Process	GO:0042060	wound healing	IMP	J:151020