GO Annotations Graph

• Symbol: Zbtb16
• Name: zinc finger and BTB domain containing 16
• ID: MGI:103222

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:73065
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:54621
Molecular Function	GO:0005515	protein binding	IPI	J:96986
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:164563
Molecular Function	GO:0031703	type 2 angiotensin receptor binding	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:109310
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISS	J:113682
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:89934
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0017053	transcription repressor complex	ISO	J:73065
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:62547
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:62547
Biological Process	GO:0051216	cartilage development	ISO	J:164563
Biological Process	GO:0008283	cell population proliferation	IMP	J:62547
Biological Process	GO:0007417	central nervous system development	IDA	J:113682
Biological Process	GO:0042733	embryonic digit morphogenesis	ISO	J:155856
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	ISO	J:155856
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:62547
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	MGI:MGI:61278
Biological Process	GO:0009880	embryonic pattern specification	IMP	J:62547
Biological Process	GO:0009880	embryonic pattern specification	IMP	J:62547
Biological Process	GO:0035136	forelimb morphogenesis	IMP	J:62547
Biological Process	GO:0030097	hemopoiesis	ISO	J:164563
Biological Process	GO:0030097	hemopoiesis	IDA	J:113682
Biological Process	GO:0035137	hindlimb morphogenesis	IMP	J:62547
Biological Process	GO:0048133	male germ-line stem cell asymmetric division	IMP	J:91129
Biological Process	GO:0048133	male germ-line stem cell asymmetric division	IMP	J:89934
Biological Process	GO:0001823	mesonephros development	IDA	J:113682
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:62547
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:73065
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:73065
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	IDA	J:113682
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0043931	ossification involved in bone maturation	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:62547
Biological Process	GO:0061036	positive regulation of cartilage development	ISO	J:164563
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045600	positive regulation of fat cell differentiation	ISO	J:164563
Biological Process	GO:0051138	positive regulation of NK T cell differentiation	IMP	J:139299
Biological Process	GO:0045778	positive regulation of ossification	ISO	J:164563
Biological Process	GO:0034504	protein localization to nucleus	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:62547
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	IMP	J:62547
Biological Process	GO:0001501	skeletal system development	IMP	MGI:MGI:61278
Biological Process	GO:0001501	skeletal system development	IMP	J:5039