GO Annotations Graph

• Symbol: Rela
• Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)
• ID: MGI:103290

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042805	actinin binding	IPI	J:221512
Molecular Function	GO:0042805	actinin binding	ISO	J:164563
Molecular Function	GO:0071532	ankyrin repeat binding	IPI	J:170429
Molecular Function	GO:0003682	chromatin binding	IDA	J:170429
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:151982
Molecular Function	GO:0003682	chromatin binding	IDA	J:215277
Molecular Function	GO:0003682	chromatin binding	IDA	J:163557
Molecular Function	GO:0003682	chromatin binding	IDA	J:151982
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:97945
Molecular Function	GO:0003677	DNA binding	IDA	J:199058
Molecular Function	GO:0003677	DNA binding	IDA	J:98564
Molecular Function	GO:0003677	DNA binding	IDA	J:89918
Molecular Function	GO:0003677	DNA binding	ISO	J:97353
Molecular Function	GO:0003677	DNA binding	IDA	J:102721
Molecular Function	GO:0003677	DNA binding	IDA	J:70298
Molecular Function	GO:0003677	DNA binding	IDA	J:138423
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:287036
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IMP	J:272425
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:86244
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:113693
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:242544
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	IPI	J:179897
Molecular Function	GO:0140296	general transcription initiation factor binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:247479
Molecular Function	GO:0042802	identical protein binding	IPI	J:149600
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:164563
Molecular Function	GO:0042277	peptide binding	ISO	J:164563
Molecular Function	GO:0042301	phosphate ion binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:201834
Molecular Function	GO:0005515	protein binding	IPI	J:171373
Molecular Function	GO:0005515	protein binding	IPI	J:179897
Molecular Function	GO:0005515	protein binding	IPI	J:163302
Molecular Function	GO:0005515	protein binding	IPI	J:163302
Molecular Function	GO:0005515	protein binding	IPI	J:200399
Molecular Function	GO:0005515	protein binding	IPI	J:247479
Molecular Function	GO:0005515	protein binding	IPI	J:272425
Molecular Function	GO:0005515	protein binding	IPI	J:247470
Molecular Function	GO:0005515	protein binding	IPI	J:175173
Molecular Function	GO:0005515	protein binding	IPI	J:175173
Molecular Function	GO:0005515	protein binding	IPI	J:174433
Molecular Function	GO:0005515	protein binding	IPI	J:190685
Molecular Function	GO:0005515	protein binding	IPI	J:162780
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:200508
Molecular Function	GO:0005515	protein binding	IPI	J:127192
Molecular Function	GO:0005515	protein binding	IPI	J:204781
Molecular Function	GO:0005515	protein binding	IPI	J:149600
Molecular Function	GO:0005515	protein binding	IPI	J:113974
Molecular Function	GO:0005515	protein binding	IPI	J:160776
Molecular Function	GO:0005515	protein binding	IPI	J:175202
Molecular Function	GO:0005515	protein binding	IPI	J:245354
Molecular Function	GO:0005515	protein binding	IPI	J:274548
Molecular Function	GO:0005515	protein binding	IPI	J:189804
Molecular Function	GO:0005515	protein binding	IPI	J:197511
Molecular Function	GO:0005515	protein binding	IPI	J:197511
Molecular Function	GO:0005515	protein binding	IPI	J:197481
Molecular Function	GO:0005515	protein binding	IPI	J:170429
Molecular Function	GO:0005515	protein binding	IPI	J:170429
Molecular Function	GO:0005515	protein binding	IPI	J:140561
Molecular Function	GO:0005515	protein binding	IPI	J:245288
Molecular Function	GO:0005515	protein binding	IPI	J:201736
Molecular Function	GO:0005515	protein binding	IPI	J:150472
Molecular Function	GO:0005515	protein binding	IPI	J:214847
Molecular Function	GO:0005515	protein binding	IPI	J:306582
Molecular Function	GO:0005515	protein binding	IPI	J:105108
Molecular Function	GO:0005515	protein binding	IPI	J:96392
Molecular Function	GO:0005515	protein binding	IPI	J:73196
Molecular Function	GO:0005515	protein binding	IPI	J:73196
Molecular Function	GO:0005515	protein binding	IPI	J:159937
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IPI	J:170429
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:287036
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:102951
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:100877
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:173973
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:21626
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:195583
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Molecular Function	GO:0140110	transcription regulator activity	IDA	J:319546
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:155856
Cellular Component	GO:0000785	chromatin	IDA	J:242544
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:170429
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:219186
Cellular Component	GO:0005737	cytoplasm	IDA	J:233964
Cellular Component	GO:0005737	cytoplasm	IDA	J:181952
Cellular Component	GO:0005737	cytoplasm	IDA	J:148250
Cellular Component	GO:0005737	cytoplasm	IDA	J:89918
Cellular Component	GO:0005737	cytoplasm	IDA	J:129312
Cellular Component	GO:0005737	cytoplasm	IDA	J:108656
Cellular Component	GO:0005737	cytoplasm	IDA	J:73196
Cellular Component	GO:0005737	cytoplasm	IDA	J:151388
Cellular Component	GO:0005737	cytoplasm	ISO	J:97353
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:75807
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0071159	NF-kappaB complex	TAS	J:179897
Cellular Component	GO:0071159	NF-kappaB complex	ISO	J:164563
Cellular Component	GO:0035525	NF-kappaB p50/p65 complex	NAS	J:233964
Cellular Component	GO:0035525	NF-kappaB p50/p65 complex	ISO	J:164563
Cellular Component	GO:0035525	NF-kappaB p50/p65 complex	TAS	J:286766
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:233964
Cellular Component	GO:0005634	nucleus	IDA	J:170429
Cellular Component	GO:0005634	nucleus	IDA	J:179897
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:286766
Cellular Component	GO:0005634	nucleus	IC	J:319546
Cellular Component	GO:0005634	nucleus	IDA	J:176455
Cellular Component	GO:0005634	nucleus	IDA	J:148250
Cellular Component	GO:0005634	nucleus	IDA	J:129312
Cellular Component	GO:0005634	nucleus	IDA	J:73196
Cellular Component	GO:0005634	nucleus	IDA	J:91804
Cellular Component	GO:0005634	nucleus	IDA	J:70298
Cellular Component	GO:0005634	nucleus	IDA	J:75807
Cellular Component	GO:0005634	nucleus	IDA	J:96405
Cellular Component	GO:0005634	nucleus	IDA	J:89918
Cellular Component	GO:0005634	nucleus	IDA	J:151388
Cellular Component	GO:0005634	nucleus	ISO	J:97353
Cellular Component	GO:0005634	nucleus	IDA	J:108656
Cellular Component	GO:0005634	nucleus	IDA	J:99289
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	TAS	J:286766
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:63099
Biological Process	GO:1904385	cellular response to angiotensin	ISO	J:164563
Biological Process	GO:0071216	cellular response to biotic stimulus	IDA	J:199058
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	IDA	J:166840
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:164563
Biological Process	GO:0071347	cellular response to interleukin-1	ISO	J:164563
Biological Process	GO:0071354	cellular response to interleukin-6	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:155856
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IEP	J:162780
Biological Process	GO:0071223	cellular response to lipoteichoic acid	ISO	J:164563
Biological Process	GO:0071316	cellular response to nicotine	ISO	J:164563
Biological Process	GO:0071224	cellular response to peptidoglycan	ISO	J:164563
Biological Process	GO:0033554	cellular response to stress	IBA	J:265628
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:155856
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IMP	J:272425
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0006952	defense response	IMP	J:63099
Biological Process	GO:0002357	defense response to tumor cell	ISO	J:164563
Biological Process	GO:0006351	DNA-templated transcription	IMP	J:272425
Biological Process	GO:0001942	hair follicle development	IMP	J:106549
Biological Process	GO:0001942	hair follicle development	IMP	J:106549
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:0006954	inflammatory response	ISO	J:164563
Biological Process	GO:0006954	inflammatory response	IBA	J:265628
Biological Process	GO:0045087	innate immune response	IBA	J:265628
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0001889	liver development	IMP	J:28390
Biological Process	GO:0043066	negative regulation of apoptotic process	IDA	J:179897
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	IDA	J:179897
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:1902894	negative regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0042177	negative regulation of protein catabolic process	IMP	J:99127
Biological Process	GO:0033234	negative regulation of protein sumoylation	IDA	J:242544
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:242544
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0007218	neuropeptide signaling pathway	ISO	J:164563
Biological Process	GO:0038061	NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0038061	NIK/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	ISO	J:73065
Biological Process	GO:1902004	positive regulation of amyloid-beta formation	IDA	J:287036
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0032332	positive regulation of chondrocyte differentiation	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:269540
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:170429
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TAS	J:63099
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:319546
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:86244
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:138423
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IDA	J:179897
Biological Process	GO:0032735	positive regulation of interleukin-12 production	IDA	J:86244
Biological Process	GO:0032757	positive regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	ISO	J:164563
Biological Process	GO:2000630	positive regulation of miRNA metabolic process	ISO	J:164563
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:155856
Biological Process	GO:1902895	positive regulation of miRNA transcription	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IDA	J:179897
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:97353
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0014040	positive regulation of Schwann cell differentiation	ISO	J:155856
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:287036
Biological Process	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	ISO	J:164563
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	ISO	J:164563
Biological Process	GO:0030163	protein catabolic process	IMP	J:99127
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0043620	regulation of DNA-templated transcription in response to stress	ISO	J:164563
Biological Process	GO:0050727	regulation of inflammatory response	IDA	J:170429
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:210175
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0009617	response to bacterium	IDA	J:96405
Biological Process	GO:0034097	response to cytokine	IBA	J:265628
Biological Process	GO:0070555	response to interleukin-1	ISO	J:164563
Biological Process	GO:0002931	response to ischemia	ISO	J:155856
Biological Process	GO:0032495	response to muramyl dipeptide	IDA	J:151388
Biological Process	GO:0035994	response to muscle stretch	IDA	J:163557
Biological Process	GO:0010033	response to organic substance	ISO	J:164563
Biological Process	GO:0010224	response to UV-B	ISO	J:164563
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	ISO	J:164563