GO Annotations Graph

• Symbol: Pon1
• Name: paraoxonase 1
• ID: MGI:103295

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0102007	acyl-L-homoserine-lactone lactonohydrolase activity	IEA	J:72245
Molecular Function	GO:0004063	aryldialkylphosphatase activity	ISO	J:164563
Molecular Function	GO:0004063	aryldialkylphosphatase activity	ISO	J:155856
Molecular Function	GO:0004063	aryldialkylphosphatase activity	IBA	J:265628
Molecular Function	GO:0004064	arylesterase activity	ISO	J:164563
Molecular Function	GO:0004064	arylesterase activity	IBA	J:265628
Molecular Function	GO:0004064	arylesterase activity	IMP	J:63392
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0008035	high-density lipoprotein particle binding	TAS	J:63392
Molecular Function	GO:0008035	high-density lipoprotein particle binding	TAS	J:56071
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0034364	high-density lipoprotein particle	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0034366	spherical high-density lipoprotein particle	ISO	J:164563
Biological Process	GO:0019439	aromatic compound catabolic process	ISO	J:164563
Biological Process	GO:0008015	blood circulation	TAS	J:56071
Biological Process	GO:0046395	carboxylic acid catabolic process	ISO	J:164563
Biological Process	GO:0008203	cholesterol metabolic process	IMP	J:63392
Biological Process	GO:0008203	cholesterol metabolic process	TAS	J:56071
Biological Process	GO:0046434	organophosphate catabolic process	ISO	J:164563
Biological Process	GO:0046470	phosphatidylcholine metabolic process	ISO	J:164563
Biological Process	GO:0051099	positive regulation of binding	ISO	J:164563
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0032411	positive regulation of transporter activity	ISO	J:164563
Biological Process	GO:1902617	response to fluoride	ISO	J:155856
Biological Process	GO:0009636	response to toxic substance	IBA	J:265628
Biological Process	GO:0009636	response to toxic substance	IMP	J:63392