GO Annotations Graph

• Symbol: Atp7b
• Name: ATPase, copper transporting, beta polypeptide
• ID: MGI:103297

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0005507	copper ion binding	ISO	J:164563
Molecular Function	GO:0005507	copper ion binding	ISO	J:155856
Molecular Function	GO:0005507	copper ion binding	IBA	J:265628
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0043682	P-type divalent copper transporter activity	ISO	J:164563
Molecular Function	GO:0043682	P-type divalent copper transporter activity	IBA	J:265628
Molecular Function	GO:0043682	P-type divalent copper transporter activity	IDA	J:114243
Molecular Function	GO:0043682	P-type divalent copper transporter activity	IDA	J:97775
Molecular Function	GO:0043682	P-type divalent copper transporter activity	IMP	J:114243
Molecular Function	GO:0140581	P-type monovalent copper transporter activity	IEA	J:72245
Molecular Function	GO:0005215	transporter activity	IEA	J:72247
Molecular Function	GO:0008270	zinc ion binding	ISO	J:155856
Cellular Component	GO:0045177	apical part of cell	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:57632
Cellular Component	GO:0016020	membrane	IDA	J:97775
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0070160	tight junction	ISO	J:155856
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:155856
Cellular Component	GO:0005802	trans-Golgi network	IBA	J:265628
Cellular Component	GO:0005802	trans-Golgi network	IDA	J:66749
Cellular Component	GO:0032588	trans-Golgi network membrane	ISO	J:164563
Biological Process	GO:0071280	cellular response to copper ion	ISO	J:155856
Biological Process	GO:0060003	copper ion export	ISO	J:155856
Biological Process	GO:0060003	copper ion export	IBA	J:265628
Biological Process	GO:0015677	copper ion import	ISO	J:164563
Biological Process	GO:0015677	copper ion import	IBA	J:265628
Biological Process	GO:0006825	copper ion transport	ISO	J:164563
Biological Process	GO:0006825	copper ion transport	IDA	J:114243
Biological Process	GO:0006825	copper ion transport	IMP	J:66749
Biological Process	GO:0006825	copper ion transport	IMP	J:114243
Biological Process	GO:0006825	copper ion transport	IDA	J:97775
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:66749
Biological Process	GO:0006878	intracellular copper ion homeostasis	IBA	J:265628
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:66749
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:19226
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:15955
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:1046
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:19226
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:44523
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:7102
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:44523
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:44523
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:57632
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:66749
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:40104
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:57632
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:57632
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:19226
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:19226
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:45933
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:44523
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:19226
Biological Process	GO:0006878	intracellular copper ion homeostasis	IMP	J:44523
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:19226
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:44523
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:19226
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:15955
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:19226
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:45933
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:44523
Biological Process	GO:0006882	intracellular zinc ion homeostasis	IMP	J:44523
Biological Process	GO:0007595	lactation	IMP	MGI:MGI:71982
Biological Process	GO:0007595	lactation	IMP	J:7102
Biological Process	GO:0007595	lactation	IMP	J:1046
Biological Process	GO:0006812	monoatomic cation transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0015680	protein maturation by copper ion transfer	IMP	J:106305
Biological Process	GO:0046688	response to copper ion	ISO	J:164563
Biological Process	GO:0051208	sequestering of calcium ion	ISO	J:164563