Cacnb4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
MGI:103301

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	TAS	J:59479
Molecular Function	GO:0005515	protein binding	IPI	J:215837
Molecular Function	GO:0005515	protein binding	IPI	J:200489
Molecular Function	GO:0005515	protein binding	IPI	J:188568
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:106959
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:49244
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:49244
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IMP	J:56225
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IDA	J:56225
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IDA	J:56225
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IDA	J:56225
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:56225
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:56225
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:56225
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:56225
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:56225
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:56225
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:56225
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:56225
Cellular Component	GO:0016607	nuclear speck	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-525831
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:164563
Cellular Component	GO:0005891	voltage-gated calcium channel complex	ISO	J:164563
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IBA	J:265628
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IMP	J:49244
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IDA	J:57712
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IMP	J:49244
Biological Process	GO:0007628	adult walking behavior	IMP	J:57712
Biological Process	GO:0007628	adult walking behavior	IMP	J:79139
Biological Process	GO:0007628	adult walking behavior	IMP	J:30226
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:60000
Biological Process	GO:0070588	calcium ion transmembrane transport	IEA	J:72247
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	IMP	J:56507
Biological Process	GO:0006816	calcium ion transport	IMP	J:29347
Biological Process	GO:0006816	calcium ion transport	IMP	J:29347
Biological Process	GO:0046058	cAMP metabolic process	IMP	J:29347
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	IMP	J:136113
Biological Process	GO:0014051	gamma-aminobutyric acid secretion	IMP	J:29347
Biological Process	GO:0014051	gamma-aminobutyric acid secretion	IMP	J:29347
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IMP	J:29786
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IMP	J:4388
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IMP	J:29786
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IMP	J:29786
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IMP	J:30226
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:95687
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0055001	muscle cell development	IMP	J:121463
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	ISO	J:155856
Biological Process	GO:0050877	nervous system process	IMP	J:1484
Biological Process	GO:0050877	nervous system process	IMP	J:43226
Biological Process	GO:0007528	neuromuscular junction development	IBA	J:265628
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:121463
Biological Process	GO:0019227	neuronal action potential propagation	IMP	J:6556
Biological Process	GO:0048541	Peyer's patch development	IMP	J:5281
Biological Process	GO:1904751	positive regulation of protein localization to nucleolus	ISO	J:155856
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	ISO	J:155856
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:95687
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:106959
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IDA	J:56225
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IDA	J:56225
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IDA	J:56225
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	IMP	J:56225
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	ISO	J:164563
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	IBA	J:265628
Biological Process	GO:0048536	spleen development	IMP	J:5281
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:56225
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:95687
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:115345
Biological Process	GO:0048538	thymus development	IMP	J:5281

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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