GO Annotations Graph

• Symbol: Bmp7
• Name: bone morphogenetic protein 7
• ID: MGI:103302

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0070700	BMP receptor binding	ISO	J:22224
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005125	cytokine activity	TAS	J:30057
Molecular Function	GO:0008083	growth factor activity	IEA	J:72247
Molecular Function	GO:0008083	growth factor activity	IEA	J:60000
Molecular Function	GO:0008201	heparin binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:86665
Molecular Function	GO:0005515	protein binding	IPI	J:97529
Molecular Function	GO:0005515	protein binding	IPI	J:87049
Molecular Function	GO:0005515	protein binding	IPI	J:98379
Molecular Function	GO:0005515	protein binding	IPI	J:83462
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:83462
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Biological Process	GO:1905069	allantois development	IGI	J:53294
Biological Process	GO:0036305	ameloblast differentiation	IDA	J:94518
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IMP	J:119026
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IMP	J:119026
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IMP	J:53380
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	IMP	J:127939
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:30057
Biological Process	GO:0007411	axon guidance	IDA	J:83462
Biological Process	GO:0030509	BMP signaling pathway	ISO	J:164563
Biological Process	GO:0030509	BMP signaling pathway	IDA	J:86665
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	IMP	J:74539
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	IDA	J:97651
Biological Process	GO:0048593	camera-type eye morphogenesis	IMP	J:103587
Biological Process	GO:0048593	camera-type eye morphogenesis	IMP	J:119026
Biological Process	GO:0048738	cardiac muscle tissue development	IGI	J:53294
Biological Process	GO:0060411	cardiac septum morphogenesis	IGI	J:53294
Biological Process	GO:0051216	cartilage development	IEA	J:60000
Biological Process	GO:0048468	cell development	IDA	J:97651
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0008283	cell population proliferation	IMP	J:119026
Biological Process	GO:0071773	cellular response to BMP stimulus	ISO	J:164563
Biological Process	GO:0060710	chorio-allantoic fusion	IGI	J:53294
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	IMP	J:53380
Biological Process	GO:0030326	embryonic limb morphogenesis	IGI	J:48538
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:48538
Biological Process	GO:0009880	embryonic pattern specification	IMP	J:53380
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	IMP	J:48538
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	IGI	J:48538
Biological Process	GO:0003272	endocardial cushion formation	IGI	J:53294
Biological Process	GO:0030855	epithelial cell differentiation	IMP	J:127939
Biological Process	GO:0001654	eye development	IMP	J:103587
Biological Process	GO:0061384	heart trabecula morphogenesis	IGI	J:53294
Biological Process	GO:0030902	hindbrain development	IGI	J:53294
Biological Process	GO:0001822	kidney development	IMP	J:103587
Biological Process	GO:1901145	mesenchymal cell apoptotic process involved in nephron morphogenesis	IMP	J:39018
Biological Process	GO:1901145	mesenchymal cell apoptotic process involved in nephron morphogenesis	IMP	J:39018
Biological Process	GO:0048762	mesenchymal cell differentiation	ISO	J:164563
Biological Process	GO:0060485	mesenchyme development	IMP	J:50004
Biological Process	GO:0001707	mesoderm formation	IGI	J:98379
Biological Process	GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	IGI	J:108109
Biological Process	GO:0072133	metanephric mesenchyme morphogenesis	IGI	J:108109
Biological Process	GO:0070487	monocyte aggregation	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045786	negative regulation of cell cycle	ISO	J:164563
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:119026
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0072125	negative regulation of glomerular mesangial cell proliferation	ISO	J:164563
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0072040	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	IMP	J:39018
Biological Process	GO:0045839	negative regulation of mitotic nuclear division	ISO	J:164563
Biological Process	GO:0050768	negative regulation of neurogenesis	IDA	J:124681
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:104282
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:104282
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	IGI	J:104840
Biological Process	GO:0042326	negative regulation of phosphorylation	ISO	J:164563
Biological Process	GO:0060686	negative regulation of prostatic bud formation	IDA	J:104840
Biological Process	GO:0072134	nephrogenic mesenchyme morphogenesis	IGI	J:108109
Biological Process	GO:0021502	neural fold elevation formation	IGI	J:53294
Biological Process	GO:0048812	neuron projection morphogenesis	ISO	J:104282
Biological Process	GO:0048812	neuron projection morphogenesis	IMP	J:104282
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IDA	J:94518
Biological Process	GO:0001503	ossification	IEA	J:60000
Biological Process	GO:0007389	pattern specification process	IMP	J:30057
Biological Process	GO:0003344	pericardium morphogenesis	IGI	J:53294
Biological Process	GO:0060037	pharyngeal system development	IGI	J:53294
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:119026
Biological Process	GO:0030501	positive regulation of bone mineralization	ISO	J:164563
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	ISO	J:164563
Biological Process	GO:1905312	positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	IGI	J:199300
Biological Process	GO:0010942	positive regulation of cell death	IGI	J:108109
Biological Process	GO:1900006	positive regulation of dendrite development	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0030858	positive regulation of epithelial cell differentiation	IDA	J:94518
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IGI	J:199300
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	ISO	J:164563
Biological Process	GO:1900106	positive regulation of hyaluranon cable assembly	ISO	J:164563
Biological Process	GO:0045666	positive regulation of neuron differentiation	IDA	J:50621
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA	J:265628
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:111703
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:111703
Biological Process	GO:0034504	protein localization to nucleus	ISO	J:164563
Biological Process	GO:0060687	regulation of branching involved in prostate gland morphogenesis	IMP	J:104840
Biological Process	GO:0060687	regulation of branching involved in prostate gland morphogenesis	IMP	J:104840
Biological Process	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	ISO	J:164563
Biological Process	GO:0042325	regulation of phosphorylation	ISO	J:155856
Biological Process	GO:0007435	salivary gland morphogenesis	IMP	J:74539
Biological Process	GO:0060395	SMAD protein signal transduction	ISO	J:164563
Biological Process	GO:0060395	SMAD protein signal transduction	IBA	J:265628
Biological Process	GO:0043401	steroid hormone mediated signaling pathway	ISO	J:164563
Biological Process	GO:0035239	tube morphogenesis	IDA	J:97651
Biological Process	GO:0001657	ureteric bud development	IMP	J:50004