Clcn3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Clcn3
chloride channel, voltage-sensitive 3
MGI:103555

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015297	antiporter activity	IDA	J:287033
Molecular Function	GO:0015297	antiporter activity	IDA	J:287048
Molecular Function	GO:0015297	antiporter activity	IDA	J:287052
Molecular Function	GO:0015297	antiporter activity	TAS	Reactome:R-MMU-2730951
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005254	chloride channel activity	ISO	J:164563
Molecular Function	GO:0005254	chloride channel activity	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:164563
Molecular Function	GO:0005247	voltage-gated chloride channel activity	ISO	J:155856
Molecular Function	GO:0005247	voltage-gated chloride channel activity	IBA	J:265628
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	IDA	J:214943
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005769	early endosome	IBA	J:265628
Cellular Component	GO:0031901	early endosome membrane	IDA	J:287043
Cellular Component	GO:0005768	endosome	IDA	J:77635
Cellular Component	GO:0010008	endosome membrane	IDA	J:287033
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:77635
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:77635
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:77635
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0060077	inhibitory synapse	ISO	J:172302
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	IDA	J:287043
Cellular Component	GO:0031902	late endosome membrane	TAS	Reactome:R-MMU-2730951
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:287052
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:287033
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0045335	phagocytic vesicle	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:287048
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:287052
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0055037	recycling endosome	IDA	J:287033
Cellular Component	GO:0055038	recycling endosome membrane	IDA	J:287052
Cellular Component	GO:0030141	secretory granule	ISO	J:164563
Cellular Component	GO:0042581	specific granule	ISO	J:164563
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:164563
Cellular Component	GO:0008021	synaptic vesicle	IBA	J:265628
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:172302
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:214943
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:164563
Cellular Component	GO:0012506	vesicle membrane	ISO	J:164563
Biological Process	GO:0008344	adult locomotory behavior	IMP	J:77635
Biological Process	GO:1902476	chloride transmembrane transport	ISO	J:164563
Biological Process	GO:0006821	chloride transport	ISO	J:155856
Biological Process	GO:0006811	monoatomic ion transport	ISO	J:155856
Biological Process	GO:0045794	negative regulation of cell volume	ISO	J:164563
Biological Process	GO:0070050	neuron cellular homeostasis	IMP	J:77635
Biological Process	GO:0006911	phagocytosis, engulfment	IMP	J:112692
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:77635
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	IMP	J:112692
Biological Process	GO:0051932	synaptic transmission, GABAergic	IMP	J:172302
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:77635
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IMP	J:172302
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IMP	J:77635
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:77635
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:77635
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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