GO Annotations Graph

• Symbol: Xpc
• Name: xeroderma pigmentosum, complementation group C
• ID: MGI:103557

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003684	damaged DNA binding	ISO	J:164563
Molecular Function	GO:0003684	damaged DNA binding	IBA	J:265628
Molecular Function	GO:0003684	damaged DNA binding	IDA	J:185050
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0140612	DNA damage sensor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:185050
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IDA	J:221330
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:221330
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0003697	single-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0000109	nucleotide-excision repair complex	ISO	J:164563
Cellular Component	GO:0000111	nucleotide-excision repair factor 2 complex	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:84299
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0090734	site of DNA damage	IDA	J:185050
Cellular Component	GO:0071942	XPC complex	ISO	J:164563
Cellular Component	GO:0071942	XPC complex	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IMP	J:88558
Biological Process	GO:0006281	DNA repair	IMP	J:80212
Biological Process	GO:0006298	mismatch repair	IBA	J:265628
Biological Process	GO:0031573	mitotic intra-S DNA damage checkpoint signaling	IGI	J:94447
Biological Process	GO:0006289	nucleotide-excision repair	ISO	J:164563
Biological Process	GO:0006289	nucleotide-excision repair	IBA	J:265628
Biological Process	GO:0006289	nucleotide-excision repair	IDA	J:185050
Biological Process	GO:0006289	nucleotide-excision repair	IMP	J:117815
Biological Process	GO:0006289	nucleotide-excision repair	IMP	J:153645
Biological Process	GO:0006289	nucleotide-excision repair	IMP	J:153645
Biological Process	GO:0006289	nucleotide-excision repair	IMP	J:153645
Biological Process	GO:0006289	nucleotide-excision repair	IMP	J:153645
Biological Process	GO:0006289	nucleotide-excision repair	IDA	J:84299
Biological Process	GO:0006289	nucleotide-excision repair	IMP	J:38645
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	IMP	J:117815
Biological Process	GO:1901990	regulation of mitotic cell cycle phase transition	ISO	J:164563
Biological Process	GO:0010224	response to UV-B	IMP	J:88558
Biological Process	GO:0070914	UV-damage excision repair	ISO	J:164563
Biological Process	GO:0070914	UV-damage excision repair	IDA	J:185050