GO Annotations Graph

• Symbol: Sox18
• Name: SRY (sex determining region Y)-box 18
• ID: MGI:103559

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:81702
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:81702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:88479
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:28005
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:61488
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:197716
Molecular Function	GO:0005515	protein binding	IPI	J:175110
Molecular Function	GO:0005515	protein binding	IPI	J:197716
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:28005
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:88479
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:143564
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:175110
Cellular Component	GO:0005634	nucleus	IC	J:81702
Cellular Component	GO:0005634	nucleus	IDA	J:143564
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:197716
Biological Process	GO:0001525	angiogenesis	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IGI	J:113127
Biological Process	GO:0001568	blood vessel development	IMP	J:61488
Biological Process	GO:0001568	blood vessel development	IMP	J:150211
Biological Process	GO:0048469	cell maturation	IDA	J:160232
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:123026
Biological Process	GO:0060956	endocardial cell differentiation	IGI	J:123026
Biological Process	GO:0060214	endocardium formation	IGI	J:123026
Biological Process	GO:0061028	establishment of endothelial barrier	ISO	J:164563
Biological Process	GO:0022405	hair cycle process	ISO	J:164563
Biological Process	GO:0001942	hair follicle development	IMP	J:66010
Biological Process	GO:0001942	hair follicle development	IMP	J:61488
Biological Process	GO:0007507	heart development	IMP	J:61488
Biological Process	GO:0001701	in utero embryonic development	IMP	J:143564
Biological Process	GO:0001701	in utero embryonic development	IMP	J:150211
Biological Process	GO:0001701	in utero embryonic development	IMP	J:61488
Biological Process	GO:0001945	lymph vessel development	IMP	J:150354
Biological Process	GO:0001945	lymph vessel development	IMP	J:6220
Biological Process	GO:0001946	lymphangiogenesis	ISO	J:164563
Biological Process	GO:0001946	lymphangiogenesis	IBA	J:265628
Biological Process	GO:0001946	lymphangiogenesis	IMP	J:143564
Biological Process	GO:0060836	lymphatic endothelial cell differentiation	IMP	J:143564
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:143564
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:175110
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:61488
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:143564
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:67559
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:88479
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:28005
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:81702
Biological Process	GO:0072091	regulation of stem cell proliferation	IDA	J:160232
Biological Process	GO:0048866	stem cell fate specification	IDA	J:160232
Biological Process	GO:0001944	vasculature development	IMP	J:150211
Biological Process	GO:0001570	vasculogenesis	IBA	J:265628
Biological Process	GO:0001570	vasculogenesis	IGI	J:113127