GO Annotations Graph

• Symbol: Kpna2
• Name: karyopherin subunit alpha 2
• ID: MGI:103561

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:240298
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0061608	nuclear import signal receptor activity	ISO	J:164563
Molecular Function	GO:0061608	nuclear import signal receptor activity	IBA	J:265628
Molecular Function	GO:0061608	nuclear import signal receptor activity	IDA	J:96792
Molecular Function	GO:0061608	nuclear import signal receptor activity	IDA	J:98705
Molecular Function	GO:0008139	nuclear localization sequence binding	ISO	J:164563
Molecular Function	GO:0008139	nuclear localization sequence binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:314556
Molecular Function	GO:0005515	protein binding	IPI	J:227344
Molecular Function	GO:0005515	protein binding	IPI	J:245384
Molecular Function	GO:0005515	protein binding	IPI	J:240298
Molecular Function	GO:0005515	protein binding	IPI	J:114101
Molecular Function	GO:0005515	protein binding	IPI	J:225620
Molecular Function	GO:0005515	protein binding	IPI	J:225415
Molecular Function	GO:0005515	protein binding	IPI	J:281212
Molecular Function	GO:0005515	protein binding	IPI	J:136267
Molecular Function	GO:0005515	protein binding	IPI	J:225487
Molecular Function	GO:0005515	protein binding	IPI	J:173031
Molecular Function	GO:0005515	protein binding	IPI	J:244973
Cellular Component	GO:0010494	cytoplasmic stress granule	IDA	J:259116
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	NAS	J:320612
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9619130
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9619142
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263467
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:263467
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263467
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263467
Cellular Component	GO:0042564	NLS-dependent protein nuclear import complex	ISO	J:164563
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	NAS	J:320612
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9619142
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IEP	J:263467
Cellular Component	GO:0014069	postsynaptic density	IDA	J:263467
Cellular Component	GO:0014069	postsynaptic density	IDA	J:263467
Cellular Component	GO:0014069	postsynaptic density	IDA	J:263467
Cellular Component	GO:0014069	postsynaptic density	IDA	J:263467
Biological Process	GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	ISO	J:241220
Biological Process	GO:0075506	entry of viral genome into host nucleus through nuclear pore complex via importin	IMP	J:241220
Biological Process	GO:0006607	NLS-bearing protein import into nucleus	ISO	J:164563
Biological Process	GO:0006607	NLS-bearing protein import into nucleus	IBA	J:265628
Biological Process	GO:1903902	positive regulation of viral life cycle	IMP	J:241220
Biological Process	GO:1903902	positive regulation of viral life cycle	ISO	J:241220
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	IDA	J:263467
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	IMP	J:263467
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	IDA	J:263467
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	IDA	J:263467
Biological Process	GO:0006606	protein import into nucleus	ISO	J:164563
Biological Process	GO:0006606	protein import into nucleus	IDA	J:98705
Biological Process	GO:0006606	protein import into nucleus	IDA	J:96792