GO Annotations Graph

• Symbol: Musk
• Name: muscle, skeletal, receptor tyrosine kinase
• ID: MGI:103581

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0030165	PDZ domain binding	IPI	J:134925
Molecular Function	GO:0005515	protein binding	IPI	J:86639
Molecular Function	GO:0005515	protein binding	IPI	J:205644
Molecular Function	GO:0005515	protein binding	IPI	J:196095
Molecular Function	GO:0005515	protein binding	IPI	J:163004
Molecular Function	GO:0005515	protein binding	IPI	J:145549
Molecular Function	GO:0005515	protein binding	IPI	J:145446
Molecular Function	GO:0005515	protein binding	IPI	J:219084
Molecular Function	GO:0005515	protein binding	IPI	J:144064
Molecular Function	GO:0005515	protein binding	IPI	J:78399
Molecular Function	GO:0005515	protein binding	IPI	J:78399
Molecular Function	GO:0005515	protein binding	IPI	J:157644
Molecular Function	GO:0005515	protein binding	IPI	J:175007
Molecular Function	GO:0005515	protein binding	IPI	J:122785
Molecular Function	GO:0005515	protein binding	IPI	J:87379
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	TAS	J:27415
Molecular Function	GO:0017147	Wnt-protein binding	IBA	J:265628
Cellular Component	GO:0042995	cell projection	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:157644
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:145549
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:144064
Cellular Component	GO:0031594	neuromuscular junction	ISO	J:155856
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:157644
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:119654
Cellular Component	GO:0005886	plasma membrane	IDA	J:145549
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-2467624
Cellular Component	GO:0005886	plasma membrane	TAS	J:27415
Cellular Component	GO:0005886	plasma membrane	IDA	J:87379
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:145549
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Cellular Component	GO:0045202	synapse	IDA	J:157644
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0060291	long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:0007613	memory	ISO	J:155856
Biological Process	GO:0097049	motor neuron apoptotic process	IMP	J:70506
Biological Process	GO:0007275	multicellular organism development	IBA	J:265628
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0007528	neuromuscular junction development	ISO	J:164563
Biological Process	GO:0007528	neuromuscular junction development	IGI	J:78399
Biological Process	GO:0007528	neuromuscular junction development	IGI	J:78399
Biological Process	GO:0007528	neuromuscular junction development	IGI	J:110011
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0033674	positive regulation of kinase activity	IBA	J:265628
Biological Process	GO:2000673	positive regulation of motor neuron apoptotic process	IMP	J:70506
Biological Process	GO:0010976	positive regulation of neuron projection development	IBA	J:265628
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:155856
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IBA	J:265628
Biological Process	GO:2000541	positive regulation of protein geranylgeranylation	IMP	J:86639
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IMP	J:86639
Biological Process	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering	IMP	J:144064
Biological Process	GO:0045887	positive regulation of synaptic assembly at neuromuscular junction	ISO	J:155856
Biological Process	GO:0032224	positive regulation of synaptic transmission, cholinergic	ISO	J:155856
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0043113	receptor clustering	ISO	J:155856
Biological Process	GO:0043113	receptor clustering	IGI	J:78399
Biological Process	GO:0043113	receptor clustering	IMP	J:69623
Biological Process	GO:0043113	receptor clustering	IGI	J:110011
Biological Process	GO:0043113	receptor clustering	IGI	J:78399
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:55315
Biological Process	GO:0008582	regulation of synaptic assembly at neuromuscular junction	IMP	J:33132
Biological Process	GO:0051602	response to electrical stimulus	ISO	J:155856
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	IMP	J:83827
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628